Influenza A virus (IAV) is a single-stranded, negative-sense RNA virus and a common cause
of seasonal flu in humans. Its genome comprises eight RNA segments that facilitate …

Emerging infectious disease threats require rapid response tools to inform diagnostics,
treatment, and outbreak control. RNA-based metagenomics offers this; however, most …

Background Q fever is a zoonotic disease caused by Coxiella burnetii infection, with
domestic ruminants as the main source of infection and tick bites as one of the transmission …

Background Recently, metagenomic next-generation sequencing (mNGS) has been used in
the diagnosis of infectious diseases (IDs) as an emerging and powerful tool. However …

Background High-throughput sequencing (HTS) technologies completed by the
bioinformatic analysis of the generated data are becoming an important detection technique …

Acute respiratory failure (ARF) is common in hematological malignancies patients, notably
those with acute leukemia, myelodysplastic syndrome, or allogeneic stem-cell …

The virome is a subpopulation of the microbiota that colonise the human body,
encompassing eukaryotic and prokaryotic viruses, which include bacteriophages. The lung …

Plant viruses are a major cause of crop losses and decreased agricultural productivity
worldwide. Rapid and accurate detection of plant viruses is essential for the implementation …

Introduction. Despite almost a century passing since the discovery of penicillin and many
years since the initiation of vaccinations against Streptococcus pneumoniae, this principal …

Background: Pneumocystis jirovecii is an opportunistic pathogen which can cause fatal
Pneumocystis pneumonia (PCP). The precise diagnosis of PCP remains challenging for its …