• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Objective To examine definitions and measures for genetic literacy in the published
literature, and the associations between commonly utilized measures. Methods We …

As cost-effective next-generation genome sequencing rapidly develops, calls for greater
inclusion of Black people in genomic research, policy, and practice are necessary for …

Over the last decades, the relevance of genetics in cardiovascular diseases has expanded,
especially in the context of cardiomyopathies. Its relevance extends to the management of …

Objective Research on family communication of germline genome sequencing (GS) results
(versus of genetic results after targeted genetic testing) is still emerging, yet potentially …

PURPOSE: Tumor genomic testing (TGT) has become increasingly adopted as part of
standard cancer care for many cancers. Despite national guidelines around patient …

First-degree relatives (FDRs) of people with rheumatoid arthritis (RA) are increasingly
recruited to prediction and prevention studies. Access to FDRs is usually via their proband …

Informed consent is crucial for participant understanding, engagement, and partnering for
research. However, current written informed consents have significant limitations …

Background: Tumor genomic testing (TGT) has become standard-of-care for most patients
with advanced/metastatic cancer. Despite established guidelines, patient education prior to …

Information generated by genomic discoveries is increasingly accessible in clinical, public
health, and direct-to-consumer contexts, reaching broader segments of the population than …