lncRNA TUG1 as potential novel biomarker for prognosis of cardiovascular diseases

H Haybar, NS Sadati, D Purrahman… - …, 2023 - Taylor & Francis
Globally, cardiovascular diseases (CVDs) are among the leading causes of death. In light of
the high prevalence and mortality of CVDs, it is imperative to understand the molecules …

[HTML][HTML] Investigating the causal effect of Dickkopf-1 on coronary artery disease and ischemic stroke: a Mendelian randomization study

PF Zheng, JJ Rong, ZF Zheng, ZY Liu, HW Pan… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Epidemiological investigations have indicated a correlation between elevated plasma levels
of Dickkopf-related protein 1 (DKK1) and the presence of atherosclerosis. However, the …

Cdon suppresses vascular smooth muscle calcification via repression of the Wnt/Runx2 Axis

BY Ahn, Y Jeong, S Kim, Y Zhang, SW Kim… - … & Molecular Medicine, 2023 - nature.com
Osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) is a risk factor
associated with vascular diseases. Wnt signaling is one of the major mechanisms implicated …

Dual inhibition of the Wnt inhibitors DKK1 and Sclerostin promotes fracture healing and increases the density and strength of uninjured bone: an experimental study in …

M Florio, PJ Kostenuik, M Stolina, FJ Asuncion… - JBJS, 2023 - journals.lww.com
Background: Fracture repair involves the reactivation of developmental signaling cascades,
including Wnt signaling that stimulates bone formation and bone regeneration. Rodent data …

Dickkopf‐1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1

X Li, T Zheng, Y Zhang, Y Zhao, F Liu, S Dai… - The FASEB …, 2023 - Wiley Online Library
Vascular smooth muscle cells (VSMCs) are considered to be a crucial source of foam cells
in atherosclerosis due to their low expression level of cholesterol exporter ATP‐binding …

Hepatic DKK1-driven steatosis is CD36 dependent

Z Yang, X Huang, J Zhang, K You… - Life science …, 2023 - life-science-alliance.org
Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide; about 25% of NAFLD
silently progress into steatohepatitis, in which some of them may develop into fibrosis …

Risk of subclinical atherosclerosis in primary Sjogren's syndrome: A systematic review and meta-analysis

P Karakasis, D Patoulias, K Pamporis… - European Journal of …, 2023 - Elsevier
Background Currently, the guidelines for prevention and management of atherosclerosis in
patients with Sjogren's syndrome (SS) do not differentiate from those concerning the general …

Endothelial Dysfunction in Cardiorenal Conditions: Implications of Endothelial Glucocorticoid Receptor-Wnt Signaling

MS Akhter, JE Goodwin - International Journal of Molecular Sciences, 2023 - mdpi.com
The endothelium constitutes the innermost lining of the blood vessels and controls blood
fluidity, vessel permeability, platelet aggregation, and vascular tone. Endothelial dysfunction …

运动改善颈动脉内膜中层厚度的研究进展

阮蔚淇, 黄伟, 翟浩男, 庄洁 - 上海预防医学, 2023 - sjpm.org.cn
动脉粥样硬化(AS) 是诱发心血管疾病(CVDs) 的主要病因, 颈动脉内膜中层厚度(cIMT) 是AS
的生物标志物. 大量研究证实, 运动能减缓甚至逆转cIMT 的形成和发展. 本文以不同运动方式 …

Molecular Linkage between Immune System Disorders and Atherosclerosis

K Napiórkowska-Baran, O Schmidt… - Current Issues in …, 2023 - mdpi.com
A strong relationship exists between immune dysfunction and cardiovascular disease.
Immune dysregulation can promote the development of cardiovascular diseases as well as …