[HTML][HTML] Nanoparticle protein corona: from structure and function to therapeutic targeting
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …
However, despite the clinical success of NP technology, it is not well-understood how NPs …
Isothermal titration calorimetry (ITC) as a promising tool in pharmaceutical nanotechnology
IDL Cavalcanti, FHX Junior, NSS Magalhães… - International Journal of …, 2023 - Elsevier
Isothermal titration calorimetry (ITC) is a technique for evaluating the thermodynamic profiles
of connection between two molecules, allowing the experimental design of nanoparticles …
of connection between two molecules, allowing the experimental design of nanoparticles …
Identification of the proteins determining the blood circulation time of nanoparticles
C Marques, MJ Hajipour, C Marets, A Oudot… - ACS …, 2023 - ACS Publications
The therapeutic efficacy and adverse impacts of nanoparticles (NPs) are strongly dependent
on their systemic circulation time. The corona proteins adsorbed on the NPs determine their …
on their systemic circulation time. The corona proteins adsorbed on the NPs determine their …
[HTML][HTML] Endosomal sorting results in a selective separation of the protein corona from nanoparticles
S Han, R da Costa Marques, J Simon… - Nature …, 2023 - nature.com
The formation of the protein corona is a well-known effect when nanoparticles (NP) are
exposed to biological environments. The protein corona is the most important factor, which …
exposed to biological environments. The protein corona is the most important factor, which …
Competition of opsonins and dysopsonins on the nanoparticle surface
The biological behavior and fate of nanoparticles are dependent on their retention time in
the blood circulation system. The protein corona components, especially opsonins, and …
the blood circulation system. The protein corona components, especially opsonins, and …