Plant-derived bioactive compounds in the management of neurodegenerative disorders: Challenges, future directions and molecular mechanisms involved in …

S Shoaib, MA Ansari, AA Fatease, AY Safhi, U Hani… - Pharmaceutics, 2023 - mdpi.com
Neurodegenerative disorders encompass a wide range of pathological conditions caused
by progressive damage to the neuronal cells and nervous-system connections, which …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial …

Y Yang, T Huang, H Zhang, X Li, S Shi, X Tian… - Phytomedicine, 2023 - Elsevier
Background Depression is a common complication after myocardial infarction (MI) that can
seriously affect the prognosis of MI. Purpose To investigate whether formononetin could …

Phytochemical Investigation of Three Cystoseira Species and Their Larvicidal Activity Supported with In Silico Studies

SH Aly, AM Elissawy, D Salah, NA Alfuhaid, OH Zyaan… - Marine Drugs, 2023 - mdpi.com
Culex pipiens mosquitoes are transmitters of many viruses and are associated with the
transmission of many diseases, such as filariasis and avian malaria, that have a high rate of …

Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and …

D Elebeedy, A Ghanem, SH Aly, MA Ali, AHI Faraag… - BMC microbiology, 2023 - Springer
Background The emergence of different viral infections calls for the development of new,
effective, and safe antiviral drugs. Glycyrrhiza glabra is a well-known herbal remedy …

Synergistic Effect of Sophora japonica and Glycyrrhiza glabra Flavonoid-Rich Fractions on Wound Healing: In Vivo and Molecular Docking Studies

SH Aly, AM Elissawy, AMA Mahmoud, FS El-Tokhy… - Molecules, 2023 - mdpi.com
Glycyrrhiza glabra and Sophora japonica (Fabaceae) are well-known medicinal plants with
valuable secondary metabolites and pharmacological properties. The flavonoid-rich …

GC/MS Profiling of the Essential Oil and Lipophilic Extract of Moricandia sinaica Boiss. and Evaluation of Their Cytotoxic and Antioxidant Activities

SH Aly, NH Kandil, RM Hemdan, SS Kotb, SS Zaki… - Molecules, 2023 - mdpi.com
The genus Moricandia (Brassicaceae) comprises about eight species that were used in
traditional medicine. Moricandia sinaica is used to alleviate certain disorders such as …

Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review

SH Aly, AMM Elbadry, M El-Shazly… - Frontiers in Natural …, 2023 - frontiersin.org
Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …

Toxicodynamics of phytonutrients

SH Aly, MA Shah, Z Chauhdary, MS Al-Ghamdi… - Phytonutrients and …, 2023 - Elsevier
Toxicodynamics defined the dynamic reciprocity of toxic phytochemical/toxicant with
biological targets and its physiological responses. As a phytochemical toxicant enters in the …

13 Brown Algae (Phaeophyta)

SH Aly, EA Elhawary, AM Elissawy… - Aquatic Medicinal …, 2023 - api.taylorfrancis.com
Seaweeds/marine macroalgae are macroscopic multicellular organisms that are usually an
important part of the ecosystem worldwide. According to Fritsch (1935), there are 11 classes …