[HTML][HTML] Overcoming the limitations of immunotherapy in pancreatic ductal adenocarcinoma: Combining radiotherapy and metabolic targeting therapy

H Zhang, W Xu, H Zhu, X Chen, H Tsai - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
As a novel anticancer therapy, immunotherapy has demonstrated robust efficacy against a
few solid tumors but poor efficacy against pancreatic ductal adenocarcinoma (PDAC). This …

Therapeutic implications of the metabolic changes associated with BRAF inhibition in melanoma

AW Loftus, M Zarei, H Kakish, O Hajihassani… - Cancer Treatment …, 2024 - Elsevier
Melanoma metabolism can be reprogrammed by activating BRAF mutations. These
mutations are present in up to 50% of cutaneous melanomas, with the most common being …

[HTML][HTML] L-glyceraldehyde inhibits neuroblastoma cell growth via a multi-modal mechanism on metabolism and signaling

M Forbes, R Kempa, G Mastrobuoni, L Rayman… - Cancers, 2024 - mdpi.com
Simple Summary Approximately half of all infants and children newly diagnosed with
neuroblastoma are at high risk for relapse despite aggressive multi-modal therapy …

In-vivo correlations of fluorescent or radioisotope glucose-analogs in imaging cancer metabolism

H Lin, M Kobayashi, K Kushiro, H Yanagie… - Nuclear Medicine …, 2024 - journals.lww.com
Objective To investigate the impact of different tracer modifications on the imaging of cancer
metabolism, focusing on the comparison of fluorescent glucose-analog tracers (2-NBDG and …

[PDF][PDF] Martin Forbes1, 3, Richard Kempa1, Guido Mastrobuoni1, Liam Rayman1, Matthias Pietzke1, 2, 4

S Bayram, B Arlt, A Spruessel, H Deubzer, S Kempa - researchgate.net
Glyceraldehyde (GA) is a 3-carbon monosaccharide that can be present in cells as a by-
product of fructose metabolism. Bruno Mendel and Otto Warburg showed that the application …