[HTML][HTML] Multi-Omics Approach to Improved Diagnosis and Treatment of Atopic Dermatitis and Psoriasis
Psoriasis and atopic dermatitis fall within the category of cutaneous immune-mediated
inflammatory diseases (IMIDs). The prevalence of IMIDs is increasing in industrialized …
inflammatory diseases (IMIDs). The prevalence of IMIDs is increasing in industrialized …
The Role of Genetics on Psoriasis Susceptibility, Comorbidities, and Treatment Response
A Bui, F Orcales, A Kranyak, BY Chung… - Dermatologic …, 2024 - derm.theclinics.com
Psoriasis is a systemic immune-mediated chronic inflammatory disease characterized by
erythematous and scaly skin plaques affecting 3.2% of adults in the United States and up to …
erythematous and scaly skin plaques affecting 3.2% of adults in the United States and up to …
Small Indels in the Androgen Receptor Gene: Phenotype Implications and Mechanisms of Mutagenesis
RM Ramos, RJ Petroli… - The Journal of …, 2024 - academic.oup.com
Context Despite high abundance of small indels in human genomes, their precise roles and
underlying mechanisms of mutagenesis in Mendelian disorders require further investigation …
underlying mechanisms of mutagenesis in Mendelian disorders require further investigation …
Genome‑wide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan
Psoriasis is a chronic inflammatory dermatological disease, and there is a lack of
understanding of the genetic factors involved in psoriasis in Taiwan. To establish …
understanding of the genetic factors involved in psoriasis in Taiwan. To establish …
Decreased TET2/5-hmC reduces the integrity of the epidermal barrier via epigenetic dysregulation of filaggrin in psoriatic lesions
H Zhang, T Jia, D Che, B Peng, Z Chu, X Song… - Journal of …, 2024 - Elsevier
Background TET2 participates in tumor progression and intrinsic immune homeostasis via
epigenetic regulation. TET2 has been reported to be involved in maintaining epithelial …
epigenetic regulation. TET2 has been reported to be involved in maintaining epithelial …