Comparison of disease severity in glaucoma patients identified by screening in the 1990s and in routine clinical care in the 2010s in Sweden

B Bengtsson, C Villalba, D Peters… - Acta …, 2024 - Wiley Online Library
Abstract Background and Purpose In a previous study comparing the amount of visual field
damage at presentation in patients having open‐angle glaucoma (OAG) identified through …

Pathological high intraocular pressure induces glial cell reactive proliferation contributing to neuroinflammation of the blood-retinal barrier via the NOX2/ET-1 axis …

X Shi, P Li, M Herb, H Liu, M Wang, X Wang… - Journal of …, 2024 - Springer
Background NADPH oxidase (NOX), a primary source of endothelial reactive oxygen
species (ROS), is considered a key event in disrupting the integrity of the blood-retinal …

The Finnish current care guideline for open‐angle glaucoma

S Leinonen, M Harju, J Hagman… - Acta …, 2024 - Wiley Online Library
This article is an English translation of the 4th Finnish Current Care Guideline for
diagnostics, treatment and follow‐up of primary open‐angle glaucoma, normal‐tension …

Effect of a fixed combination of ripasudil and brimonidine on aqueous humor dynamics in mice

R Yamagishi-Kimura, M Honjo, M Aihara - Scientific Reports, 2024 - nature.com
Ripasudil–brimonidine fixed-dose combination (K-232) simultaneously targets three
different intraocular pressure (IOP) lowering mechanisms, increasing trabecular meshwork …

Remyelination‐oriented clemastine treatment attenuates neuropathies of optic nerve and retina in glaucoma

K Liu, Y Yang, Z Wu, C Sun, Y Su, N Huang, H Wu, C Yi… - Glia, 2024 - Wiley Online Library
As one of the top causes of blindness worldwide, glaucoma leads to diverse optic
neuropathies such as degeneration of retinal ganglion cells (RGCs). It is widely accepted …

The Impact of Baseline Intraocular Pressure on Initial Treatment Response in the LiGHT Trial: Selective Laser Trabeculoplasty versus Medication.

ET Fahy, G Montesano, A Garg, V Vickerstaff… - Ophthalmology, 2024 - Elsevier
Purpose The Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial demonstrated the
efficacy and safety of selective laser trabeculoplasty (SLT) compared to topical hypotensive …

[HTML][HTML] Frequency of Agreement Between Structural and Functional Glaucoma Testing: A Longitudinal Study of 3D OCT and Current Clinical Tests

D Manik, K Ratanawongphaibul, J Kim… - American Journal of …, 2024 - Elsevier
Purpose To evaluate how often tests of structure and function detect glaucoma progression
at the same study visit. Tests include current glaucoma clinical tests and a new 3 …

Association of Long-Term Intraocular Pressure Variability and Rate of Ganglion Complex Thinning in Patients With Glaucoma

G Mahmoudinezhad, S Moghimi, T Nishida… - American Journal of …, 2024 - Elsevier
Purpose To evaluate the association of mean intraocular pressure (IOP) and IOP variability
(IOP fluctuation [SD of IOP] and the IOP range) with the rate of ganglion cell complex (GCC) …

Intraocular pressure increases the rate of macular vessel density loss in glaucoma

G Mahmoudinezhad, S Moghimi, T Nishida… - British Journal of …, 2024 - bjo.bmj.com
Background/aims To evaluate the relationship over time between intraocular pressure (IOP)
and the rate of macula whole image vessel density (wiVD) loss and whole image ganglion …

A Randomized, Controlled Comparison of NCX 470, a Nitric Oxide-Donating Bimatoprost, and Latanoprost in Subjects with Open-Angle Glaucoma or Ocular …

R Fechtner, S Mansberger, J Branch, J Mulaney… - American Journal of …, 2024 - Elsevier
Purpose To compare intraocular pressure (IOP)-lowering efficacy and safety of NCX 470, a
nitric oxide (NO)-donating bimatoprost, to latanoprost in subjects with open-angle glaucoma …