Reassessing the exon–foldon correspondence using frustration analysis

EA Galpern, H Jaafari, C Bueno, PG Wolynes… - Proceedings of the …, 2024 - pnas.org
Protein folding and evolution are intimately linked phenomena. Here, we revisit the concept
of exons as potential protein folding modules across a set of 38 abundant and conserved …

[PDF][PDF] Hana Jaafari

P Wolynes - 2024 - repository.rice.edu
Proteins serve as the machinery for cellular function. Proteins and protein complexes help
cellular systems maintain homeostasis and respond to environmental cues. Proper protein …

Evolutionary Fitness of Non-Coding Genetic Elements

H Jaafari - 2024 - search.proquest.com
Proper protein structure and function are integral to cellular homeostasis. The wide array of
known natural protein sequences are a product of millions of years of evolutionary pressure …

Degree of protein structure disorder in prokaryotic and eukaryotic organisms

Z Nováková - 2024 - dspace.cuni.cz
The structure-function paradigm of protein biology has been fundamentally changed in the
last three decades by the discovery of intrinsically disordered proteins (IDPs) and regions …