Criteria for Diagnosis and Molecular Monitoring of NPM1-Mutated AML
NPM1-mutated acute myeloid leukemia (AML) represents the largest molecular subgroup of
adult AML. NPM1-mutated AML is recognizable by molecular techniques and …
adult AML. NPM1-mutated AML is recognizable by molecular techniques and …
Innovations in conditioning and post-transplant maintenance in AML: genomically informed revelations on the graft-versus-leukemia effect
HM Murdock, VT Ho, JS Garcia - Frontiers in Immunology, 2024 - frontiersin.org
Acute Myeloid Leukemia (AML) is the prototype of cancer genomics as it was the first
published cancer genome. Large-scale next generation/massively parallel sequencing …
published cancer genome. Large-scale next generation/massively parallel sequencing …
Prophylactic maintenance with venetoclax/azacitidine after reduced-intensity conditioning allogeneic transplant for high-risk MDS and AML
JS Garcia, HT Kim, HM Murdock, M Ansuinelli… - Blood …, 2024 - ashpublications.org
We conducted a phase 1 trial assessing safety and efficacy of prophylactic maintenance
therapy with venetoclax and azacitidine (Ven/Aza) for patients with high-risk myelodysplastic …
therapy with venetoclax and azacitidine (Ven/Aza) for patients with high-risk myelodysplastic …
Smart Conditioning with Venetoclax-Enhanced Sequential FLAMSA+ RIC in Patients with High-Risk Myeloid Malignancies
F Schulz, P Jäger, J Tischer, A Fraccaroli, G Bug… - Cancers, 2024 - mdpi.com
Simple Summary Allogeneic stem cell transplantation (aHSCT) is the only potentially
curative treatment option for patients with high-risk myeloid malignancies. Depending on the …
curative treatment option for patients with high-risk myeloid malignancies. Depending on the …
Test then erase? Current status and future opportunities for Measurable Residual Disease testing in Acute Myeloid Leukemia
AL Blackmon, CS Hourigan - Acta haematologica, 2024 - karger.com
Background: Measurable residual disease (MRD) test positivity during and after treatment in
patients with acute myeloid leukemia (AML) has been associated with higher rates of …
patients with acute myeloid leukemia (AML) has been associated with higher rates of …
Hematopoietic cell transplantation (HCT) in MDS patients of older age
C Niederwieser, N Kröger - Leukemia & Lymphoma, 2024 - Taylor & Francis
Hematopoietic cell transplantation (HCT) has evolved to an essential treatment in younger
and more recently in elderly patients with myelodysplastic syndrome (MDS), the age group …
and more recently in elderly patients with myelodysplastic syndrome (MDS), the age group …
Strategies to reduce relapse risk in patients undergoing allogeneic stem cell transplantation for acute myeloid leukaemia
FAM Kinsella, MAL Maroto, J Loke… - British Journal of …, 2024 - Wiley Online Library
Allogeneic stem cell transplantation is a centrally important curative strategy in adults with
acute myeloid leukaemia; however, relapse occurs in a significant proportion of patients and …
acute myeloid leukaemia; however, relapse occurs in a significant proportion of patients and …
Venetoclax-based treatment in acute myeloid leukemia: an unexpected bonus on the path to allogeneic hematopoietic stem cell transplant?
F Tarantini, C Cumbo, L Anelli, A Zagaria… - Leukemia & …, 2024 - Taylor & Francis
Despite the approval of new drugs, the inclusion of-omics-derived data and the integration of
machine learning in both the diagnostic and therapeutic process, the prognosis of acute …
machine learning in both the diagnostic and therapeutic process, the prognosis of acute …