Over the last decade, the comorbidity between Autism Spectrum Disorder (ASD) and
epilepsy has been widely demonstrated, and many hypotheses regarding the common …

Children are much more susceptible to the neurotoxic effects of organophosphate (OP)
pesticides and nerve agents than adults. OP poisoning in children leads to acute seizures …

Single-molecule imaging techniques have revealed the dynamic nature of ion channels and
shown that channel activity is sometimes dependent on their mobility and mechanical forces …

Organophosphates (OPs) and nerve agents are potent neurotoxic compounds that cause
seizures, status epilepticus (SE), brain injury, or death. There are persistent long-term …

Background Alzheimer's disease (AD) is associated with gradual memory loss and anxiety
which affects~ 75% of AD patients. This study investigated whether AD‐associated anxiety …

Previously, we demonstrated that palmatine (PALM)–an isoquinoline alkaloid from Berberis
sibrica radix, exerted antiseizure activity in the pentylenetetrazole (PTZ)-induced seizure …

Parvalbumin expressing (PV+) GABAergic interneurons are fast spiking neurons that
provide powerful but relatively short-lived inhibition to principal excitatory cells in the brain …

Parvalbumin-positive (PV+) interneurons are GABAergic neurons found in various brain
regions, with unique morphological and physiological traits (Hijazi et al., 2023). These …

Epilepsy is a common neurological disorder, which lacks a comprehensive understanding of
epileptogenesis. Temporal lobe epilepsy (TLE) in particular, often involves the …

Os transtornos psiquiátricos são as comorbidades mais frequentes na epilepsia e exercem
uma interferência significativa na qualidade de vida dos pacientes. Dentre as manifestações …