Targeting the Warburg Effect in Cancer: Where Do We Stand?

I Barba, L Carrillo-Bosch, J Seoane - International Journal of Molecular …, 2024 - mdpi.com
The Warburg effect, characterized by the preferential conversion of glucose to lactate even
in the presence of oxygen and functional mitochondria, is a prominent metabolic hallmark of …

Shikonin reverses cancer-associated fibroblast-induced gemcitabine resistance in pancreatic cancer cells by suppressing monocarboxylate transporter 4-mediated …

X Hu, X Peng, Y Zhang, S Fan, X Liu, Y Song, S Ren… - Phytomedicine, 2024 - Elsevier
Background Gemcitabine is a first-line chemotherapeutic agent for pancreatic cancer (PC);
however, most patients who receive adjuvant gemcitabine rapidly develop resistance and …

[HTML][HTML] Exploring monocarboxylate transporter inhibition for cancer treatment

T Koltai, L Fliegel - Exploration of Targeted Anti-tumor Therapy, 2024 - ncbi.nlm.nih.gov
Cells are separated from the environment by a lipid bilayer membrane that is relatively
impermeable to solutes. The transport of ions and small molecules across this membrane is …

Identification of hypoxia‐induced metabolism‐associated genes in canine tumours

T Kato, M Sakurai, K Watanabe… - Veterinary and …, 2024 - Wiley Online Library
Canine tumours including urothelial carcinoma, lung adenocarcinoma, mammary gland
tumour, squamous cell carcinoma, and melanoma have been identified as causes of death …

SARS-CoV-2 infection associated cell entry proteins ACE2, CD147, PPIA, and PPIB as potential prognostic and infection biomarkers in neuroblastoma

B Bergsneider, E Bailey, Y Ahmed, N Gogineni… - 2024 - authorea.com
Introduction: Although most children experience minor symptoms from SARS-CoV-2
infection, some develop complications including MIS-C. Neuroblastoma patients may be at …