Shaping immunity: The influence of natural selection on population immune diversity

HE Randolph, KA Aracena, YL Lin, Z Mu… - Immunological …, 2024 - Wiley Online Library
Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …

Evolutionary plant–pollinator responses to anthropogenic land‐use change: impacts on ecosystem services

M Pontarp, A Runemark, M Friberg… - Biological …, 2024 - Wiley Online Library
Agricultural intensification at field and landscape scales, including increased use of
agrochemicals and loss of semi‐natural habitats, is a major driver of insect declines and …

[HTML][HTML] Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

D Kotliar, S Raju, S Tabrizi, I Odia, A Goba… - Nature …, 2024 - nature.com
Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an
estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here …

[HTML][HTML] The selection landscape and genetic legacy of ancient Eurasians

EK Irving-Pease, A Refoyo-Martínez, W Barrie… - Nature, 2024 - nature.com
Abstract The Holocene (beginning around 12,000 years ago) encompassed some of the
most significant changes in human evolution, with far-reaching consequences for the …

selscan 2.0: scanning for sweeps in unphased data

ZA Szpiech - Bioinformatics, 2024 - academic.oup.com
Several popular haplotype-based statistics for identifying recent or ongoing positive
selection in genomes require knowledge of haplotype phase. Here, we provide an update to …

[HTML][HTML] Human pangenome analysis of sequences missing from the reference genome reveals their widespread evolutionary, phenotypic, and functional roles

Z Wu, T Li, Z Jiang, J Zheng, Y Gu, Y Liu… - Nucleic Acids …, 2024 - academic.oup.com
Nonreference sequences (NRSs) are DNA sequences present in global populations but
absent in the current human reference genome. However, the extent and functional …

Genomic evidence for evolutionary history and local adaptation of two endemic apricots: Prunus hongpingensis and P. zhengheensis

X Dai, S Xiang, Y Zhang, S Yang, Q Hu… - Horticulture …, 2024 - academic.oup.com
Apricot, belonging to the Armeniaca section of Rosaceae, is one of the economically
important crop fruits that has been extensively cultivated. The natural wild apricots offer …

[HTML][HTML] Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution

X Zhang, M Blaxter, JMD Wood, A Tracey… - Nature …, 2024 - nature.com
Abstract Theory predicts that compensatory genetic changes reduce negative indirect effects
of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a …

Deciphering climate resilience in Indian cattle breeds by selection signature analyses

SS Nayak, M Panigrahi, D Rajawat, K Ghildiyal… - Tropical Animal Health …, 2024 - Springer
The signature of selection is a crucial concept in evolutionary biology that refers to the
pattern of genetic variation which arises in a population due to natural selection. In the …

A repertoire of single nucleotide polymorphisms (SNPs) of major fecundity BMPR1B gene among 75 sheep breeds worldwide

C Cao, Q Zhou, Y Kang, Z Akhatayeva, P Liu, Y Bai… - Theriogenology, 2024 - Elsevier
The BMPR1B gene is a major determinant of sheep reproductive capacity. Previous studies
revealed that Q249R (FecB) is a profound variant of BMPR1B that influences the ovulation …