Shaping immunity: The influence of natural selection on population immune diversity
Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …
challenges. Such variation is widespread and affects individual and population‐level …
Evolutionary plant–pollinator responses to anthropogenic land‐use change: impacts on ecosystem services
Agricultural intensification at field and landscape scales, including increased use of
agrochemicals and loss of semi‐natural habitats, is a major driver of insect declines and …
agrochemicals and loss of semi‐natural habitats, is a major driver of insect declines and …
[HTML][HTML] Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever
Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an
estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here …
estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here …
[HTML][HTML] The selection landscape and genetic legacy of ancient Eurasians
Abstract The Holocene (beginning around 12,000 years ago) encompassed some of the
most significant changes in human evolution, with far-reaching consequences for the …
most significant changes in human evolution, with far-reaching consequences for the …
selscan 2.0: scanning for sweeps in unphased data
ZA Szpiech - Bioinformatics, 2024 - academic.oup.com
Several popular haplotype-based statistics for identifying recent or ongoing positive
selection in genomes require knowledge of haplotype phase. Here, we provide an update to …
selection in genomes require knowledge of haplotype phase. Here, we provide an update to …
[HTML][HTML] Human pangenome analysis of sequences missing from the reference genome reveals their widespread evolutionary, phenotypic, and functional roles
Z Wu, T Li, Z Jiang, J Zheng, Y Gu, Y Liu… - Nucleic Acids …, 2024 - academic.oup.com
Nonreference sequences (NRSs) are DNA sequences present in global populations but
absent in the current human reference genome. However, the extent and functional …
absent in the current human reference genome. However, the extent and functional …
Genomic evidence for evolutionary history and local adaptation of two endemic apricots: Prunus hongpingensis and P. zhengheensis
X Dai, S Xiang, Y Zhang, S Yang, Q Hu… - Horticulture …, 2024 - academic.oup.com
Apricot, belonging to the Armeniaca section of Rosaceae, is one of the economically
important crop fruits that has been extensively cultivated. The natural wild apricots offer …
important crop fruits that has been extensively cultivated. The natural wild apricots offer …
[HTML][HTML] Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution
Abstract Theory predicts that compensatory genetic changes reduce negative indirect effects
of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a …
of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a …
Deciphering climate resilience in Indian cattle breeds by selection signature analyses
SS Nayak, M Panigrahi, D Rajawat, K Ghildiyal… - Tropical Animal Health …, 2024 - Springer
The signature of selection is a crucial concept in evolutionary biology that refers to the
pattern of genetic variation which arises in a population due to natural selection. In the …
pattern of genetic variation which arises in a population due to natural selection. In the …
A repertoire of single nucleotide polymorphisms (SNPs) of major fecundity BMPR1B gene among 75 sheep breeds worldwide
C Cao, Q Zhou, Y Kang, Z Akhatayeva, P Liu, Y Bai… - Theriogenology, 2024 - Elsevier
The BMPR1B gene is a major determinant of sheep reproductive capacity. Previous studies
revealed that Q249R (FecB) is a profound variant of BMPR1B that influences the ovulation …
revealed that Q249R (FecB) is a profound variant of BMPR1B that influences the ovulation …