Interactions between macromolecules, such as proteins and nucleic acids, are essential for
cellular functions. Experimental methods can fail to provide all the information required to …

Molecular docking is a computational method based on bioinformatics that simulates the
interaction dynamics of molecules such as ligands and receptors, predicting their binding …

The lasting threat of viral pandemics necessitates the development of tailorable first-
response antivirals with specific but adaptive architectures for treatment of novel viral …

In plant leaves, starch is composed of glucan polymers that accumulate in chloroplasts as
the products of photosynthesis during the day; starch is mobilized at night to continuously …

An important element of antibody-guided vaccine design is the use of neutralizing or
opsonic monoclonal antibodies to define protective epitopes in their native three …

The mitochondrial serine protease HtrA2 is a human homolog of the Escherichia coli Deg-
proteins exhibiting chaperone and proteolytic roles. HtrA2 is involved in both apoptotic …

To biosynthesize ribosomally synthesized and post-translationally modified peptides
(RiPPs), enzymes recognize and bind to the N-terminal leader region of substrate peptides …

The SERF family of proteins were originally discovered for their ability to accelerate amyloid
formation. Znf706 is an uncharacterized protein whose N-terminus is homologous to SERF …

Maintenance of ploidy depends on the mitotic kinase Aurora B, the catalytic subunit of the
chromosomal passenger complex (CPC) whose proficient activity is supported by HP1 …

This study developed a novel protein–protein docking approach based on quantum
chemistry. To judge the appropriateness of complex structures, we introduced two criterion …