The Role of the Nuclear Factor-Kappa B (NF-κB) Pathway in SARS-CoV-2 Infection

P Kesika, S Thangaleela, N Sisubalan, A Radha… - Pathogens, 2024 - mdpi.com
COVID-19 is a global health threat caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is associated with a significant increase in morbidity and …

Flavonoid-rich sesame leaf extract-mediated synthesis of nanozymes: Extraction optimization, chemical composition identification and bioactivity evaluation

R Zhang, Y Liu, Y Gao, D Peng, Q Luan, Z Li, X Xia… - Food Chemistry, 2024 - Elsevier
Sesame leaves contain rich phenolic acids and flavonoids. However, their potential in
nanozyme synthesis has not been investigated yet. Herein, we report the preparation of …

A newly identified scallop MyD88 interacts with TLR and functions in innate immunity

B Huang, J Ma, W Xu, J Cui, J Chen, Y Qu… - Fish & Shellfish …, 2024 - Elsevier
Abstract Myeloid differentiation factor-88 (MyD88) is a key adaptor of the toll-like receptor
(TLR) signaling pathway and plays a crucial role in innate immune signal transduction in …

Expanding strategies to resolve psoriasis-like inflammation: Non-canonical NF-κB signaling controls IL-23 production in dendritic cells

T Neuwirth, G Stary - Molecular Therapy, 2024 - cell.com
Inflammation is a crucial process employed by the immune system to control pathogens and
other invading stimuli. After clearance, inflammation is resolved and controlled by multiple …

Analysis of the binding pattern of NIK inhibitors by computational simulation

Y Tang - Journal of Biomolecular Structure and Dynamics, 2024 - Taylor & Francis
Abstract NF-kappaB-Inducing Kinase (NIK) is a key kinase in the activation of the NF-κB non-
classical signalling pathway, which has been shown to be over-activated in patients with …

[HTML][HTML] Inhibitory effects of SARS-CoV-2 spike protein and BNT162b2 vaccine on erythropoietin-induced globin gene expression in erythroid precursor cells from …

LC Cosenza, G Marzaro, M Zurlo, J Gasparello… - Experimental …, 2024 - Elsevier
During the recent coronavirus disease 2019 (COVID-19) pandemic several patients with β-
thalassemia have been infected by severe acute respiratory syndrome coronavirus (SARS …

The Interplay of the TLR-NFκB Signalling Pathway and Functional Enzymes in the LPS Inflammatory Response of Ciona robusta

L Bisanti, C La Corte, M Dara, F Bertini, J Vizioli… - 2024 - preprints.org
Abstract the close phylogenetic relationship between ascidians (Tunicata) and vertebrates
makes them a powerful model for studying the innate immune system. To better understand …

Catechin, Epicatechin and Quercetin against Gamma-irradiation-induced Nrf-2, Nf-kB and Antioxidant Enzymes alterations in Cellular System of Rats

OK BELLO, MO Salawu, JA Samuel, O Henrietta… - 2024 - researchsquare.com
Background: Cell are prone to oxidative insults that are mediated by Rats exposure to
gamma (γ) irradiation. These insult are nuclear factor kappa-B (Nf-kB) mediated, but the …