[HTML][HTML] Advancing Personalized Medicine in Neurodegenerative Diseases: The Role of epigenetics and pharmacoepigenomics in Pharmacotherapy

C Griñán-Ferré, A Bellver-Sanchis, A Guerrero… - Pharmacological …, 2024 - Elsevier
About 80% of brain disorders have a genetic basis. The pathogenesis of most
neurodegenerative diseases is associated with a myriad of genetic defects, epigenetic …

Repeated binge‐like eating episodes in female rats alter adenosine A2A and dopamine D2 receptor genes regulation in the brain reward system

F Mercante, E Micioni Di Bonaventura… - … Journal of Eating …, 2024 - Wiley Online Library
Objective Binge‐eating disorder is an eating disorder characterized by recurrent binge‐
eating episodes, during which individuals consume excessive amounts of highly palatable …

[HTML][HTML] Dietary regulation of silent synapses in the dorsolateral striatum

AM Meyers, F Gnazzo, ED Barrera, T Nabatian, L Chan… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Obesity results in circuit adaptations that closely resemble those induced by drugs of abuse.
AMPA-lacking 'silent'synapses are critical in circuit generation during early development, but …