The suprachiasmatic nucleus at 50: looking back, then looking forward

D Ono, DR Weaver, MH Hastings… - Journal of biological …, 2024 - journals.sagepub.com
It has been 50 years since the suprachiasmatic nucleus (SCN) was first identified as the
central circadian clock and 25 years since the last overview of developments in the field was …

Eating Around the Clock: Circadian Rhythms of Eating and Metabolism

AW McHill, MP Butler - Annual Review of Nutrition, 2024 - annualreviews.org
The time of day that we eat is increasingly recognized as contributing as importantly to
overall health as the amount or quality of the food we eat. The endogenous circadian clock …

Clock gene homologs lin-42 and kin-20 regulate circadian rhythms in C. elegans

ML Lamberti, RK Spangler, V Cerdeira, M Ares… - Scientific Reports, 2024 - nature.com
Circadian rhythms are endogenous oscillations in nearly all organisms, from prokaryotes to
humans, allowing them to adapt to cyclical environments for close to 24 h. Circadian rhythms …

[HTML][HTML] Reflections on Several Landmark Advances in Circadian Biology

S Chawla, H Oster, GE Duffield, E Maronde… - Journal of circadian …, 2024 - ncbi.nlm.nih.gov
Circadian Biology intersects with diverse scientific domains, intricately woven into the fabric
of organismal physiology and behavior. The rhythmic orchestration of life by the circadian …

More than the clock: distinct regulation of muscle function and metabolism by PER2 and RORα

S Mansingh, G Maier, J Delezie… - The Journal of …, 2024 - Wiley Online Library
Circadian rhythms, governed by the dominant central clock, in addition to various peripheral
clocks, regulate almost all biological processes, including sleep–wake cycles, hormone …

Variants in the circadian clock genes PER2 and PER3 associate with familial sleep phase disorders

L Plavc, C Skubic, L Dolenc Grošelj… - Chronobiology …, 2024 - Taylor & Francis
Delayed sleep phase disorder and advanced sleep phase disorder cause disruption of the
circadian clock and present with extreme morning/evening chronotype with unclear role of …

[HTML][HTML] Fighting Against the Clock: Circadian Disruption and Parkinson's Disease

YC Chen, WS Wang, SJG Lewis… - Journal of Movement …, 2024 - ncbi.nlm.nih.gov
Circadian disruption is being increasingly recognized as a critical factor in the development
and progression of Parkinson's disease (PD). This review aims to provide an in-depth …

蝙蝠核心生物钟基因Per1 昼夜表达节律与适应性进化研究

王慧, 许宁宁, 李昕彤, 冯江 - 兽类学报, 2024 - mammal.cn
长期以来, 生物钟相关研究一直是生命科学领域的热点话题. 以往研究表明核心生物钟基因Per1
广泛参与哺乳动物昼夜节律调控. 然而, Per1 基因在具有不同昼夜节律活动模式的哺乳动物中 …

A mixed effects cosinor modelling framework for circadian gene expression

MT Gorczyca - arXiv preprint arXiv:2405.01450, 2024 - arxiv.org
The cosinor model is frequently used to represent gene expression given the 24 hour day-
night cycle time at which a corresponding tissue sample is collected. However, the timing of …

Heavy Metals Remediation in Plants Through Genetic Tools: A Boon for Mankind

A Dey, D Das, B Mondal, T Roychowdhury - Metals and Metalloids in Plant …, 2024 - Springer
There have been a lot of instances where the plants are getting affected by heavy metals
and metalloid toxicity. Due to contamination of heavy metals for the soil, green leafy …