[HTML][HTML] DNA G-quadruplexes as Targets for Natural Product Drug Discovery

KB Wang, Y Wang, J Dickerhoff, D Yang - Engineering, 2024 - Elsevier
Abstract DNA G-quadruplexes (G4s) are unique secondary structures formed by two or more
stacked G-tetrads in G-rich DNA sequences. These structures have been found to play a …

Probing the binding and interaction of curcumin-tryptophan conjugate to G-quadruplex motif via spectroscopic and molecular docking approach

AK Dwivedi, NS Jha - Journal of Molecular Structure, 2024 - Elsevier
A potential ligand with the ability to interact with the structure of G-quadruplexes has been
promising strategy for develop anticancer drug. Curcumin, a natural antioxidant is known to …