Cell Membrane Perforation: Patterns, Mechanisms and Functions

X Zhu, Z Shi, Y Mao, U Lächelt, R Huang - Small, 2024 - Wiley Online Library
Cell membrane is crucial for the cellular activities, and any disruption to it may affect the
cells. It is demonstrated that cell membrane perforation is associated with some biological …

Progress and future of the computational design of antimicrobial peptides (AMPs): bio-inspired functional molecules

M Nedyalkova, AS Paluch, DP Vecini, M Lattuada - Digital Discovery, 2024 - pubs.rsc.org
The effectiveness of antibiotics is greatly enhanced by their ability to target invasive
organisms involved in the ancient evolutionary battle between hosts and pathogens …

Assembly-Induced Membrane Selectivity of Artificial Model Peptides through Entropy–Enthalpy Competition

L Wei, W Tu, Y Xu, C Xu, Y Dou, Y Ge, S Sun, Y Wei… - ACS …, 2024 - ACS Publications
Peptide design and drug development offer a promising solution for combating serious
diseases or infections. In this study, using an AI–human negotiation approach, we have …