Structure, topology, and stability of multiple g-quadruplexes in long telomeric overhangs

S Shiekh, SG Kodikara, H Balci - Journal of Molecular Biology, 2024 - Elsevier
Telomeres and their single stranded overhangs gradually shorten with successive cell
divisions, as part of the natural aging process, but can be elongated by telomerase, a …

Sandwich-type aptamer-based biosensors for thrombin detection

SS Samani, E Sameiyan, FT Yazdi, SA Mortazavi… - Analytical …, 2024 - pubs.rsc.org
Thrombin, a proteolytic enzyme, plays an essential role in catalyzing many blood clotting
reactions. Thrombin can act as a marker for some blood-related diseases, such as leukemia …

Arginine-Modified Hemin Enhances G-Quadruplex DNAzyme Peroxidase Activity for High Sensitivity Detection

B Liu, T Wang, D Qiu, X Yan, Y Liu, JL Mergny… - Analytical …, 2024 - ACS Publications
Hemin/G-quadruplex (hG4) complexes are frequently used as artificial peroxidase-like
enzymatic systems (termed G4 DNAzymes) in many biosensing applications, in spite of a …

Cyclodextrin-activated porphyrin-DNA nanofibers with AS1411/Hemin toehold for enhanced and targeted photodynamic therapy

J Gao, H Yang, C Deng, Y Lv, S Liu, Z Zhao - European Polymer Journal, 2024 - Elsevier
Targeted photodynamic therapy is considered superior to conventional photodynamic
therapy due to the enhanced uptake of photosensitizers by tumor cells. However, porphyrin …