Single cell RNA-sequencing (scRNA-seq) advancements have helped detect transcriptional
heterogeneities in biological samples. However, scRNA-seq cannot currently provide high …

Spatial transcriptomics (ST) has demonstrated enormous potential for generating intricate
molecular maps of cells within tissues. Here we present iStar, a method based on …

Recent technological developments in spatial transcriptomics allow researchers to measure
gene expression of cells and their spatial locations at the single-cell level, generating …

Cardiac macrophages represent a functionally diverse population of cells involved in
cardiac homeostasis, repair, and remodeling. With recent advancements in single-cell …

The development of spatial transcriptome sequencing technology has revolutionized our
comprehension of complex tissues and propelled life and health sciences into an era of …

Aplasia cutis congenita (ACC) is a congenital epidermal defect of the midline scalp and has
been proposed to be due to a primary keratinocyte abnormality. Why it forms mainly at this …

The heart, which is the first organ to develop, is highly dependent on its form to function,.
However, how diverse cardiac cell types spatially coordinate to create the complex …

Spatially resolved transcriptomics has revolutionized RNA studies by aligning RNA
abundance with tissue structure, enabling direct comparisons between histology and gene …

Single-cell data integration can provide a comprehensive molecular view of cells, and many
algorithms have been developed to remove unwanted technical or biological variations and …

The molecular organization of the human neocortex historically has been studied in the
context of its histological layers. However, emerging spatial transcriptomic technologies …