Pancreatic epithelial IL-17/IL-17RA signaling drives B7-H4 expression to promote tumorigenesis

S Castro-Pando, RM Howell, L Li, M Mascaro… - Cancer Immunology …, 2024 - AACR
IL-17 is required for the initiation and progression of pancreatic cancer, particularly in the
context of inflammation, as previously shown by genetic and pharmacological approaches …

RGC-32 mediates proinflammatory and profibrotic pathways in immune-mediated kidney disease

A Tatomir, S Vlaicu, V Nguyen, IG Luzina, SP Atamas… - Clinical …, 2024 - Elsevier
Systemic lupus erythematosus is an autoimmune disease that results in immune-mediated
damage to kidneys and other organs. We investigated the role of response gene to …