Enhanced STAT3/PIK3R1/mTOR Signaling Triggers Tubular Cell Inflammation and Apoptosis in Septic-Induced Acute Kidney Injury: Implications for Therapeutic …

Y Fu, Y Xiang, J Zha, G Chen, Z Dong - Clinical Science, 2024 - portlandpress.com
Septic acute kidney injury (AKI) is a severe form of renal dysfunction associated with high
morbidity and mortality rates. However, the pathophysiological mechanisms underlying …

Myeloid-derived suppressor cells promote allograft survival by suppressing regulatory T cell dysfunction in high-risk corneal transplantation

S Lee, T Blanco, A Musayeva, S Dehghani… - American Journal of …, 2024 - Elsevier
Highly inflamed and neovascularized corneal graft beds are known as high-risk (HR)
environments for transplant survival. One of the primary factors leading to this rejection is …

Early life vaccination reprograms the metabolism and function of myeloid cells in neonates

Y Chen, H Li, J Zhou - Immunology, 2024 - Wiley Online Library
Vaccination after birth provides protection against pathogen infection and immune related
disorders in healthy children. The detailed effects of vaccination on neonatal immunity …

[PDF][PDF] The effect of adoptive transferring myeloid-derived suppressor cells in ventilator-induced lung injury mice

F Shan, F Tang, Y Liu, X Han, W Wu, Y Tang, Q Zhan… - Heliyon, 2024 - cell.com
The effects of adoptive transferring myeloid-derived suppressor cells (MDSCs) to mice with
ventilator-induced lung injury (VILI) are unclear. Our objective was to investigate the effects …