Development of supramolecular anticoagulants with on-demand reversibility
Drugs are administered at a dosing schedule set by their therapeutic index, and termination
of action is achieved by clearance and metabolism of the drug. In some cases, such as …
of action is achieved by clearance and metabolism of the drug. In some cases, such as …
Azole reagents enabled ligation of peptide acyl pyrazoles for chemical protein synthesis
P Liao, C He - Chemical Science, 2024 - pubs.rsc.org
Native chemical ligation (NCL) has been playing an increasingly important role in chemical
protein synthesis (CPS). More efficient ligation methods that circumvent the requirement of a …
protein synthesis (CPS). More efficient ligation methods that circumvent the requirement of a …