Whispering-gallery mode optoplasmonic microcavities: From advanced single-molecule sensors and microlasers to applications in synthetic biology

MC Houghton, SV Kashanian, TL Derrien… - ACS …, 2024 - ACS Publications
Optical microcavities, specifically, whispering-gallery mode (WGM) microcavities, with their
remarkable sensitivity to environmental changes, have been extensively employed as …

Lipid Microfluidic Biomimetic Models for Drug Screening: A Comprehensive Review

E Fernandes, VF Cardoso… - Advanced Functional …, 2024 - Wiley Online Library
Developing new drugs is a complex, time‐consuming, and expensive process, essential to
identify potential pharmacokinetic issues in the early stages to avoid investment in …

Unraveling mechanisms of protein encapsulation and release in coacervates via molecular dynamics and machine learning

Y Wang, R Zou, Y Zhou, Y Zheng, C Peng, Y Liu… - Chemical …, 2024 - pubs.rsc.org
Coacervates play a pivotal role in protein-based drug delivery research, yet their drug
encapsulation and release mechanisms remain poorly understood. Here, we utilized the …

Artificial cells with viscoadaptive behavior based on hydrogel-loaded giant unilamellar vesicles

A Llopis-Lorente, MJG Schotman, HV Humeniuk… - Chemical …, 2024 - pubs.rsc.org
Viscoadaptation is an essential process in natural cells, where supramolecular interactions
between cytosolic components drive adaptation of the cellular mechanical features to …

Nucleated synthetic cells with genetically driven intercompartment communication

IA Ioannou, C Monck, F Ceroni, NJ Brooks… - Proceedings of the …, 2024 - pnas.org
Eukaryotic cells are characterized by multiple chemically distinct compartments, one of the
most notable being the nucleus. Within these compartments, there is a continuous exchange …

Multicompartmented nanostructures with tunable interior complexities co-assembled by two plant proteins

W Zhang, Y Wan, C Xue, Z Chen, R Wang… - Chemical Engineering …, 2024 - Elsevier
Multicompartmented nanostructures, which mirror the complexity of living cells, are
promising for bio-related applications. However, controlling the spatial arrangement within …

Multi-compartment liposomes forge new paths in drug delivery

QTH Shubhra - Nature Chemistry, 2024 - nature.com
Liposomal systems frequently face challenges, such as low encapsulation efficiency and
inadequate controlled release capabilities. Innovatively designed multi-compartment …

Redefining drug therapy: innovative approaches using catalytic compartments

YL Mustafa, A Balestri, X Huang… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Rapid excretion of drug derivatives often results in short drug half-lives,
necessitating frequent administrations. Catalytic compartments, also known as nano-and …

Physicochemical control of solvation and molecular assembly of charged amphiphilic oligomers at air-aqueous interfaces

Z Liu, L Lin, T Li, UI Premadasa, K Hong, YZ Ma… - Journal of Colloid and …, 2024 - Elsevier
Hypothesis: Understanding the rules that control the assembly of nanostructured soft
materials at interfaces is central to many applications. We hypothesize that electrolytes can …

A comprehensive review of Microfluidic approaches in cell-free synthetic biology

AK Baranwal, SJ Maerkl - Frontiers in Synthetic Biology, 2024 - frontiersin.org
Cell-free synthetic biology has gained increasing popularity owing to its ability to elucidate
biological functions in isolation from intricate cellular environments and the capacity to build …