Disrupted phase behavior of FUS underlies poly-PR-induced DNA damage in amyotrophic lateral sclerosis
Y Wang, L Liu, H Chen, Y Yang, C Mu… - Human Molecular …, 2024 - academic.oup.com
Abstract GGGGCC (G4C2) hexanucleotide repeat expansion (HRE) in the first intron of the
chromosome 9 open reading frame 72 (C9ORF72) gene is the most common genetic cause …
chromosome 9 open reading frame 72 (C9ORF72) gene is the most common genetic cause …
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
J Zang, Y Wu, X Su, K Cai, M Ke, N He, H Zhu… - Advanced …, 2024 - Wiley Online Library
Small extracellular vesicles (sEVs) contain abundant circular RNAs (circRNAs) and are
involved in cellular processes, particularly hypoxia. However, the process that packaging of …
involved in cellular processes, particularly hypoxia. However, the process that packaging of …
[PDF][PDF] On the limits of inferring biophysical parameters of RBP-RNA interactions from in vitro RNA Bind'n Seq data
N Schlusser, M Zavolan - F1000Research, 2024 - f1000research.com
We develop a thermodynamic model describing the binding of RNA binding proteins (RBP)
to oligomers in vitro. We apply expectation-maximization to infer the specificity of RBPs …
to oligomers in vitro. We apply expectation-maximization to infer the specificity of RBPs …