Decoding the molecular concerto: Toxicotranscriptomic evaluation of microplastic and nanoplastic impacts on aquatic organisms

SSUH Kazmi, M Tayyab, P Pastorino, D Barcelò… - Journal of hazardous …, 2024 - Elsevier
The pervasive and steadily increasing presence of microplastics/nanoplastics (MPs/NPs) in
aquatic environments has raised significant concerns regarding their potential adverse …

Rules and impacts of nonsense‐mediated mRNA decay in the degradation of long noncoding RNAs

AK Singh - Wiley Interdisciplinary Reviews: RNA, 2024 - Wiley Online Library
Nonsense‐mediated mRNA decay (NMD) is a quality‐control process that selectively
degrades mRNAs having premature termination codon, upstream open reading frame, or …

Social fear extinction susceptibility is associated with Microbiota-Gut-Brain axis alterations

NL Ritz, TFS Bastiaanssen, CSM Cowan… - Brain, Behavior, and …, 2024 - Elsevier
Social anxiety disorder is a common psychiatric condition that severely affects individual
quality of life and is a significant societal burden. Although many risk factors for social …

The role of non-coding RNAs in muscle aging: regulatory mechanisms and therapeutic potential

YJ Shin, KS Kwon, Y Suh, KP Lee - Frontiers in Molecular …, 2024 - frontiersin.org
Muscle aging is a complex physiological process that leads to the progressive decline in
muscle mass and function, contributing to debilitating conditions in the elderly such as …

Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway

P Wei, K Tian, H Liu, K Li, N Alam, D Cheng… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Intimal hyperplasia (IH) is a common pathological feature of vascular proliferative diseases,
such as atherosclerosis and restenosis after angioplasty. Urotensin II (UII) and its receptor …

Small but mighty: the rise of microprotein biology in neuroscience

EE Duffy, EG Assad, BT Kalish… - Frontiers in Molecular …, 2024 - frontiersin.org
The mammalian central nervous system coordinates a network of signaling pathways and
cellular interactions, which enable a myriad of complex cognitive and physiological …

LncRNA CCRR maintains Ca2+ homeostasis against myocardial infarction through the FTO-SERCA2a pathway

H Yang, L Xuan, S Wang, H Luo, X Duan, J Guo… - Science China Life …, 2024 - Springer
Cardiac conduction regulatory RNA (CCRR) has been documented as an antiarrhythmic
lncRNA in our earlier investigation. This study aimed to evaluate the effects of CCRR on …

Microscale marvels: unveiling the macroscopic significance of micropeptides in human health

D Das, S Podder - Briefings in Functional Genomics, 2024 - academic.oup.com
Non-coding RNA encodes micropeptides from small open reading frames located within the
RNA. Interestingly, these micropeptides are involved in a variety of functions within the body …

LncRNA U90926 is dispensable for the development of obesity‐associated phenotypes in vivo

B Sabikunnahar, S Caldwell, S Varnum… - Physiological …, 2024 - Wiley Online Library
Obesity is a global health problem characterized by excessive fat accumulation, driven by
adipogenesis and lipid accumulation. Long non‐coding RNAs (lncRNAs) have recently …

Exploring the enigma: history, present, and future of long non-coding RNAs in cancer

QA Naseer, A Malik, F Zhang, S Chen - Discover Oncology, 2024 - Springer
Long noncoding RNAs (lncRNAs), which are more than 200 nucleotides in length and do
not encode proteins, play crucial roles in governing gene expression at both the …