Fluorescence-based detection: A review of current and emerging techniques to unveil micro/nanoplastics in environmental samples

S Morgana, B Casentini, V Tirelli, F Grasso… - TrAC Trends in …, 2024 - Elsevier
Plastic pollution represents a global environmental issue with relevant associated risks for
ecosystem and human health. Fluorescence-based detection techniques allowed rapid …

Passive microfluidic devices for cell separation

T Zhang, D Di Carlo, CT Lim, T Zhou, G Tian… - Biotechnology …, 2024 - Elsevier
The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …

Deep learning predictions of TCR-epitope interactions reveal epitope-specific chains in dual alpha T cells

G Croce, S Bobisse, DL Moreno, J Schmidt… - Nature …, 2024 - nature.com
T cells have the ability to eliminate infected and cancer cells and play an essential role in
cancer immunotherapy. T cell activation is elicited by the binding of the T cell receptor (TCR) …

High-dimensional single-cell multimodal landscape of human carotid atherosclerosis

AC Bashore, H Yan, C Xue, LY Zhu, E Kim… - … and Vascular Biology, 2024 - Am Heart Assoc
BACKGROUND: Atherosclerotic plaques are complex tissues composed of a
heterogeneous mixture of cells. However, our understanding of the comprehensive …

TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf

Y Chang, L Bach, M Hasiuk, L Wen, T Elmzzahi… - Science …, 2024 - science.org
T follicular helper (TFH) cells are essential for effective antibody responses, but deciphering
the intrinsic wiring of mouse TFH cells has long been hampered by the lack of a reliable …

Antibiotics treatment promotes vasculogenesis in the brain of glioma-bearing mice

M Rosito, J Maqbool, A Reccagni, O Giampaoli… - Cell Death & …, 2024 - nature.com
In recent years, several studies described the close relationship between the composition of
gut microbiota and brain functions, highlighting the importance of gut-derived metabolites in …

Light-field flow cytometry for high-resolution, volumetric and multiparametric 3D single-cell analysis

X Hua, K Han, B Mandracchia, A Radmand… - Nature …, 2024 - nature.com
Imaging flow cytometry (IFC) combines flow cytometry and fluorescence microscopy to
enable high-throughput, multiparametric single-cell analysis with rich spatial details …

Macrophage barrier in the tumor microenvironment and potential clinical applications

S Ji, Y Shi, B Yin - Cell Communication and Signaling, 2024 - Springer
The tumor microenvironment (TME) constitutes a complex microenvironment comprising a
diverse array of immune cells and stromal components. Within this intricate context, tumor …

Competitive fungal commensalism mitigates candidiasis pathology

J Sekeresova Kralova, C Donic, B Dassa… - Journal of Experimental …, 2024 - rupress.org
The mycobiota are a critical part of the gut microbiome, but host–fungal interactions and
specific functional contributions of commensal fungi to host fitness remain incompletely …

In vivo real-time positron emission particle tracking (PEPT) and single particle PET

J Pellico, L Vass, A Carrascal-Miniño, F Man… - Nature …, 2024 - nature.com
Positron emission particle tracking (PEPT) enables 3D localization and tracking of single
positron-emitting radiolabelled particles with high spatiotemporal resolution. The translation …