Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review
Purpose 177Lu-labelled somatostatin analog DOTATATE is an excellent vector for systemic
radiation therapy in NETs. However, this treatment can affect organ functions or impact the …
radiation therapy in NETs. However, this treatment can affect organ functions or impact the …
[HTML][HTML] Peptide Receptor Radionuclide Therapy of Neuroendocrine Tumors: Agonist, Antagonist and Alternatives
G Santo, G Di Santo, I Virgolini - Seminars in Nuclear Medicine, 2024 - Elsevier
Peptide receptor radionuclide therapy (PRRT) today is a well-established treatment strategy
for patients with neuroendocrine tumors (NET). First performed already more than 30 years …
for patients with neuroendocrine tumors (NET). First performed already more than 30 years …
[HTML][HTML] Long-term Nephrotoxicity after PRRT: Myth or Reality
Rationale: The kidneys are commonly considered as the potential dose-limiting organ for
peptide receptor radionuclide therapy (PRRT), making the risk of nephrotoxicity a primary …
peptide receptor radionuclide therapy (PRRT), making the risk of nephrotoxicity a primary …
[HTML][HTML] Toward individualized dosimetry for radiopharmaceutical therapy in day-to-day clinical practice of nuclear oncology: overcoming heterogeneity of radiation …
L Bodei, R Michael Tuttle, RK Grewal… - European Journal of …, 2024 - Springer
Radioactive iodine-131 (RAI) therapy of metastatic well-differentiated thyroid cancer (mDTC)
has been a cornerstone of nuclear medicine practice since it was first conceptualized in the …
has been a cornerstone of nuclear medicine practice since it was first conceptualized in the …
[HTML][HTML] Impact of different models based on blood samples and images for bone marrow dosimetry after 177Lu-labeled somatostatin-receptor therapy
D Vallot, S Brillouet, S Pondard, L Vija, JS Texier… - EJNMMI physics, 2024 - Springer
Background Peptide receptor radionuclide therapy with 177Lu-DOTATATE is a recognized
option for treating neuroendocrine tumors and has few toxicities, except for the kidneys and …
option for treating neuroendocrine tumors and has few toxicities, except for the kidneys and …
[HTML][HTML] A review of 177Lu dosimetry workflows: how to reduce the imaging workloads?
L Vergnaud, YK Dewaraja, AL Giraudet, JN Badel… - EJNMMI physics, 2024 - Springer
Abstract 177 Lu radiopharmaceutical therapy is a standardized systemic treatment, with a
typical dose of 7.4 GBq per injection, but its response varies from patient to patient …
typical dose of 7.4 GBq per injection, but its response varies from patient to patient …
[HTML][HTML] Prediction of [177Lu]Lu-DOTA-TATE therapy response using the absorbed dose estimated from [177Lu]Lu-DOTA-TATE SPECT/CT in patients with …
Background Peptide receptor radionuclide therapy (PRRT) with [177Lu] Lu-DOTA-TATE has
shown efficacy in patients with metastatic neuroendocrine tumours (NETs). Personalised …
shown efficacy in patients with metastatic neuroendocrine tumours (NETs). Personalised …
[HTML][HTML] Improvements of 177Lu SPECT images from sparsely acquired projections by reconstruction with deep-learning-generated synthetic projections
E Wikberg, M Essen, T Rydén, J Svensson, P Gjertsson… - EJNMMI physics, 2024 - Springer
Background For dosimetry, the demand for whole-body SPECT/CT imaging, which require
long acquisition durations with dual-head Anger cameras, is increasing. Here we evaluated …
long acquisition durations with dual-head Anger cameras, is increasing. Here we evaluated …
[HTML][HTML] Estimation of kidney doses from [177Lu]Lu-DOTA-TATE PRRT using single time point post-treatment SPECT/CT
S Spink, D Gillett, S Heard, I Harper, R Casey, L Aloj - EJNMMI physics, 2024 - Springer
Abstract Background Dosimetry after [177Lu] Lu-DOTA-TATE therapy can be demanding for
both patients and the clinical service due to the need for imaging at several time points. In …
both patients and the clinical service due to the need for imaging at several time points. In …
Kidney dosimetry in [177Lu] Lu-DOTA-TATE therapy based on multiple small VOIs
SC Kapidzic, J Gustafsson, E Larsson, L Jessen… - Physica Medica, 2024 - Elsevier
Purpose The aim was to investigate the use of multiple small VOIs for kidney dosimetry in
[177 Lu] Lu-DOTA-TATE therapy. Method The study was based on patient and simulated …
[177 Lu] Lu-DOTA-TATE therapy. Method The study was based on patient and simulated …