Transcriptional regulation via the NF-κB signaling module

[HTML][HTML] A large deletion in a non-coding regulatory region leads to NFKB1 haploinsufficiency in two adult siblings

M Fusaro, C Coustal, L Barnabei, Q Riller, M Heller… - Clinical …, 2024 - Elsevier

Mutations in NFkB pathway genes can cause inborn errors of immunity (IEI), with NFKB1
haploinsufficiency being a significant etiology for common variable immunodeficiency …

被引用次数：1 相关文章所有 3 个版本

Nuclear Factor Kappa B: A Nobel Therapeutic Target of Flavonoids Against Parkinson's Disease

NK Singh, A Singh - Combinatorial Chemistry & High …, 2024 - ingentaconnect.com

Parkinson's disease (PD), the most common brain-related neurodegenerative disorder, is
comprised of several pathophysiological mechanisms, such as mitochondrial dysfunction …

[HTML][HTML] Sulforaphane-mediated immune regulation through inhibition of NF-kB and MAPK signaling pathways in human dendritic cells

AM Múnera-Rodríguez, C Leiva-Castro… - Biomedicine & …, 2024 - Elsevier

Inflammation and immune responses are intricately intertwined processes crucial for
maintaining homeostasis and combating against pathogens. These processes involve …

GSK3β/NF-κB -dependent transcriptional regulation of homeostatic hepatocyte Tnf production

MR Grayck, WC McCarthy, M Solar… - American Journal …, 2024 - journals.physiology.org

Maintenance of hepatocyte homeostasis plays an important role in mediating the
pathogenesis of many diseases. A growing body of literature has established a critical role …

SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1

H Wang, W Chen, Y Wang, Y Gao, Z Zhang… - Science China Life …, 2024 - Springer

Metastasis accounts for the major cause of colorectal cancer (CRC) related mortality due to
the lack of effective treatments. In this study, we integrated the single-cell RNA-seq (scRNA …

Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation

Y Xu, M Dong, C Sun, Y Wang, N Zhao, K Yu, N Lu… - Toxicology Letters, 2024 - Elsevier

Ricin toxin (RT) is highly cytotoxic and can release a considerable amount of pro-
inflammatory factors due to depurination, causing excessive inflammation that may …

LncRNA MTC-p65 Protein Mediates Skin Fibroblast Proliferation in Liaoning Cashmere Goat by Regulating the Nuclear Factor-Kappa B Signaling Pathway

M Jin, X Qiu, J Piao, J Piao, F Zhao, M Cao - Biochemical Genetics, 2024 - Springer

The aim of this study is to investigate the activation of NF-κB signaling pathway and the
regulation of the expression of genes related to chorionic villus growth by the binding of …