Glioblastoma and brain connectivity: the need for a paradigm shift

A Salvalaggio, L Pini, A Bertoldo… - The Lancet Neurology, 2024 - thelancet.com
Despite substantial advances in cancer treatment, for patients with glioblastoma prognosis
remains bleak. The emerging field of cancer neuroscience reveals intricate functional …

A framework for quantifying the coupling between brain connectivity and heartbeat dynamics: Insights into the disrupted network physiology in Parkinson's disease

D Candia‐Rivera, M Vidailhet, M Chavez… - Human Brain …, 2024 - Wiley Online Library
Parkinson's disease (PD) often shows disrupted brain connectivity and autonomic
dysfunctions, progressing alongside with motor and cognitive decline. Recently, PD has …

Impaired topological properties of cortical morphological brain networks correlate with motor symptoms in Parkinson's disease

S Yan, J Lu, Y Li, T Tian, Y Zhou, H Zhu, Y Qin… - Journal of …, 2024 - Elsevier
Background Parkinson's disease (PD) is characterized by loss of selectively vulnerable
neurons within the basal ganglia circuit and progressive atrophy in subcortical and cortical …

Glucose-6-Phosphatase-Dehydrogenase activity as modulative association between Parkinson's disease and periodontitis

O Laugisch, MC Ruppert-Jungck… - Frontiers in cellular …, 2024 - frontiersin.org
The association between periodontitis (PD) and Parkinson's disease (PK) is discussed due
to the inflammatory component of neurodegenerative processes. PK severity and affected …

Random forest analysis of midbrain hypometabolism using [18F]-FDG PET identifies Parkinson's disease at the subject-level

MC Ruppert-Junck, G Kräling, A Greuel… - Frontiers in …, 2024 - frontiersin.org
Parkinson's disease (PD) is currently diagnosed largely on the basis of expert judgement
with neuroimaging serving only as a supportive tool. In a recent study, we identified a …

[HTML][HTML] The functional brain connectome in isolated rapid eye movement sleep behavior disorder and Parkinson's disease

F Holtbernd, C Hohenfeld, WH Oertel, S Knake, E Sittig… - Sleep Medicine, 2024 - Elsevier
Background Isolated rapid-eye-movement behavior disorder (iRBD) often precedes the
development of alpha-synucleinopathies such as Parkinson's disease (PD). Magnetic …

Iron and neuromelanin imaging in basal ganglia circuitry in Parkinson's disease with freezing of gait

Y Zhang, C Zhang, X Wang, Y Liu, Z Jin… - Magnetic Resonance …, 2024 - Elsevier
Objective This study aimed to examine the structural alterations of the deep gray matter
(DGM) in the basal ganglia circuitry of Parkinson's disease (PD) patients with freezing of gait …

The onset of motor learning impairments in Parkinson's disease: a computational investigation

I Gigi, R Senatore, A Marcelli - Brain Informatics, 2024 - Springer
The basal ganglia (BG) is part of a basic feedback circuit regulating cortical function, such as
voluntary movements control, via their influence on thalamocortical projections. BG …

Striato-cortical functional connectivity changes in mild cognitive impairment with Lewy bodies

L Novakova, M Gajdos, M Barton, L Brabenec… - Parkinsonism & Related …, 2024 - Elsevier
Background Functional connectivity changes in clinically overt neurodegenerative diseases
such as dementia with Lewy bodies have been described, but studies on connectivity …

Differential influences of rest tremor on brain fiber architecture in essential tremor and Parkinson's disease

X Duanmu, J Wen, J Qin, S Tan, C Wu, W Yuan… - Parkinsonism & Related …, 2024 - Elsevier
Background Rest tremor is a movement disorder commonly found in diseases like
Parkinson's disease (PD) and essential tremor (ET). Rest tremor typically shows slower …