[HTML][HTML] Endothelin and the tumor microenvironment: a finger in every pie

PF Arndt, K Turkowski, MJ Cekay, B Eul… - Clinical …, 2024 - portlandpress.com
The tumor microenvironment (TME) plays a central role in the development of cancer. Within
this complex milieu, the endothelin (ET) system plays a key role by triggering epithelial-to …

[HTML][HTML] Non-invasive biomarkers for differentiating alcohol associated hepatitis from acute decompensation in patients with ALD

M Ignat, H Stefanescu - Journal of Clinical Medicine, 2024 - mdpi.com
Alcohol-associated hepatitis (AH) is the most severe form of alcohol-related liver disease.
The natural course of alcohol-related liver disease is influenced by heavy alcohol …

[HTML][HTML] Regulation of the HIF switch in human endothelial and cancer cells

J Slawski, M Jaśkiewicz, A Barton, S Kozioł… - European Journal of …, 2024 - Elsevier
Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome
for cells to survive hypoxic insults and oxidative stress. They are important during embryonic …

[HTML][HTML] Biological factors driving colorectal cancer metastasis

SX An, ZJ Yu, C Fu, MJ Wei… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Approximately 20% of colorectal cancer (CRC) patients present with metastasis at
diagnosis. Among Stage I-III CRC patients who undergo surgical resection, 18% typically …

Nutritional and microbiota-based therapeutic intervention for alcohol-associated liver disease: Pathogenesis to therapeutic insights

S Rangra, D Rana, A Prajapati, D Benival, P Dwivedi… - Life Sciences, 2024 - Elsevier
Alcohol-associated liver disease (ALD) manifests as a consequence of prolonged and
excessive alcohol consumption. This disease is closely associated with the interplay …

Role of MicroRNAs in Alcohol-Related Liver Disease

P Nelaturi, SP Kademani, KS Nallagangula… - Alcoholism Treatment …, 2024 - Taylor & Francis
Alcohol-related liver disease (ARLD) is the most prevalent type of chronic liver disease and
one of the most serious health problems worldwide. Individuals consuming more than 40 g …