The lymphatic system possesses the main viral replication sites in the body following viral
infection. Unfortunately, current antiretroviral agents penetrate the lymph nodes insufficiently …

The success of long-acting (LA) drug delivery systems (DDSs) is linked to their
biocompatible polymers. These are used for extended therapeutic release. For treatment or …

In the present scenario, the SARS-CoV-2 virus has imposed enormous damage on human
survival and the global financial system. It has been estimated that around 111 million …

Prolonging the residence time of drugs in the lumen and propelling them into deep lesions
are highly desired for intraluminal drug administration. However, rapid drug efflux caused by …

An extended action fostemsavir (FTR) lipid nanoparticle (LNP) formulation prevents human
immunodeficiency virus type one (HIV-1) infection. This FTR formulation establishes a drug …

A significant gap exists in the demand for safe and effective drugs for inflammatory bowel
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …

Glioblastoma (GBM) is hard to treat due to cellular invasion into functioning brain tissues,
limited drug delivery, and evolved treatment resistance. Recurrence is nearly universal even …

Pharmaceutical drugs, including vaccines, pre‐and post‐exposure prophylactics, and
chronic drug therapies, are crucial tools in the prevention and treatment of infectious …

Nanocrystals refer to materials with at least one dimension smaller than 100 nm, composing
of atoms arranged in single crystals or polycrystals. Nanocrystals have significant research …

Integrating lipid conjugation strategies into the design of nucleoside monophosphate and
monophosphonate prodrugs is a well-established approach for discovering potential …