Understanding exosomes: Part 1—Characterization, quantification and isolation techniques
RJ Miron, Y Zhang - Periodontology 2000, 2024 - Wiley Online Library
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with a diameter in the range of 30–150 nm. Their use has gained great momentum recently …
with a diameter in the range of 30–150 nm. Their use has gained great momentum recently …
Multiparametric single-vesicle flow cytometry resolves extracellular vesicle heterogeneity and reveals selective regulation of biogenesis and cargo distribution
AK von Lersner, F Fernandes, PMM Ozawa… - ACS …, 2024 - ACS Publications
Mammalian cells release a heterogeneous array of extracellular vesicles (EVs) that
contribute to intercellular communication by means of the cargo that they carry. To resolve …
contribute to intercellular communication by means of the cargo that they carry. To resolve …
Targeted exosome-based nanoplatform for new-generation therapeutic strategies
W Yin, H Ma, Y Qu, S Wang, R Zhao, Y Yang… - Biomedical …, 2024 - iopscience.iop.org
Abstract Exosomes, typically 30–150 nm in size, are lipid-bilayered small-membrane
vesicles originating in endosomes. Exosome biogenesis is regulated by the coordination of …
vesicles originating in endosomes. Exosome biogenesis is regulated by the coordination of …
Size matters: Functional differences of small extracellular vesicle subpopulations in cardiac repair responses
SI van de Wakker, J Bauzá‐Martinez… - Journal of …, 2024 - Wiley Online Library
Cardiac progenitor cell (CPC)‐derived small extracellular vesicles (sEVs) exhibit great
potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity …
potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity …
Herb Extracellular Vesicle-Chitosan-PEGylated Graphene Oxide Conjugate Delivers Estrogen Receptor α Targeting siRNA to Breast Cancer Cells
Herb-based extracellular vesicles (EV), inherently replete with bioactive proteins, RNA,
lipids, and other medicinal compounds, are noncytotoxic and uniquely capable of cellular …
lipids, and other medicinal compounds, are noncytotoxic and uniquely capable of cellular …
Swelling, Rupture and Endosomal Escape of Biological Nanoparticles Per Se and Those Fused with Liposomes in Acidic Environment
N Ponomareva, S Brezgin, I Karandashov… - Pharmaceutics, 2024 - mdpi.com
Biological nanoparticles (NPs), such as extracellular vesicles (EVs), exosome-mimetic
nanovesicles (EMNVs) and nanoghosts (NGs), are perspective non-viral delivery vehicles …
nanovesicles (EMNVs) and nanoghosts (NGs), are perspective non-viral delivery vehicles …
Janus kinase inhibitors modify the fatty acid profile of extracellular vesicles and modulate the immune response
Background Janus kinase inhibitors (jakinibs) are immunomodulators used for treating
malignancies, autoimmune diseases, and immunodeficiencies. However, they induce …
malignancies, autoimmune diseases, and immunodeficiencies. However, they induce …
Development of Liposomes Loaded with Chloroaluminum Phthalocyanine for Application of Photodynamic Therapy in Breast Cancer
KAB Nogueira, AVF Reis, YS de Oliveira… - Journal of …, 2024 - Elsevier
Chloraluminium phthalocyanine (ClAlPc) has potential therapeutic effect for the treatment of
cancer; however, the molecule is lipophilic and may present self-aggregation which limits its …
cancer; however, the molecule is lipophilic and may present self-aggregation which limits its …
[HTML][HTML] Impact of donor pool size on the variability of platelet lysate-derived extracellular vesicles for regenerative medicine
AM Amengual-Tugores, C Ráez-Meseguer… - Extracellular Vesicles …, 2024 - oaepublish.com
Aim: The objective of the present study was to determine the variability of platelet lysate-
derived extracellular vesicles (pEV), in terms of characteristics and functionality through …
derived extracellular vesicles (pEV), in terms of characteristics and functionality through …
Extracellular Vesicles: The Challenges on the Way and Engineering Perspectives
Extracellular vesicles (EVs) are found in every body fluid and are known to be released by
every human cell. So far, EVs have been classified into three subclasses: Exosomes …
every human cell. So far, EVs have been classified into three subclasses: Exosomes …