Mycobacterium tuberculosis is considered by many to be the deadliest microbe, with the
estimated annual cases numbering more than 10 million. The bacteria, including …

Background In 2021, an estimated 4800 people developed rifampicin-resistant tuberculosis
in Mozambique, 75% of which went undiagnosed. Detailed molecular data on rifampicin …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a significant global
health challenge, further compounded by the issue of antimicrobial resistance (AMR). AMR …

Potential Mycobacterium tuberculosis (Mtb) transmission during different pulmonary
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …

Background Emerging resistance to bedaquiline (BDQ) threatens to undermine advances in
the treatment of drug-resistant tuberculosis (DRTB). Characterizing serial Mycobacterium …

Background Bacterial diversity could contribute to the diversity of tuberculosis infection and
treatment outcomes observed clinically, but the biological basis of this association is poorly …

The Haarlem family belongs to the Euro-American phylogenetic lineage of Mycobacterium
tuberculosis and is one of the globally spread genotypes of this important human pathogen …

Background We sought to identify resistance patterns and key drivers of recent multidrug-
resistant tuberculosis (MDR-TB) transmission in a TB-prevalent area in Peru. Methods Cross …

Rationale: The persistent burden of TB disease emphasizes the need to identify individuals
with TB for treatment and those at a high risk of incident TB for prevention. Targeting …

Background The genetic diversity of Mycobacterium tuberculosis complex (MTBC) strains
was characterized among isolates from individuals with pulmonary tuberculosis (PTB) …