The past two decades have witnessed a rapid progress in the development of surface
charge‐reversible nanoparticles (NPs) for drug delivery and diagnosis. These NPs are able …

The delivery of a drug to a specific organ or tissue at an efficacious concentration is the
pharmacokinetic (PK) hallmark of promoting effective pharmacological action at a target site …

In situ mineralization is a promising strategy to mimic the physicochemical properties of
biominerals and is widely applied in the field of bone repair. Given the high requirement for …

This study aimed to investigate the effect of phosphorylation modification of collagen peptide
on its calcium-binding capacity and pro-mineralization activity. In this study, collagen peptide …

The clinical utility of bone morphogenetic protein 2 (BMP2) is limited because of the poor
attraction between BMP2 and carriers, resulting in low loading efficiency and initial burst …

Osteomyelitis induced by Staphylococcus aureus (S. aureus) is a persistent and deep-
seated infection that affects bone tissue. The main challenges in treating osteomyelitis …

Personalized bone-regenerative materials have attracted substantial interest in recent years.
Modern clinical settings demand the use of engineered materials incorporating patient …

Enzymes play a key role in natural mineralization, but their function is disabling in bone
metabolism when patients suffer severe degenerations like hypophosphatasia. To regulate …

Developing high‐efficiency artificial biocatalysts for scavenging reactive oxygen species
(ROS) is critical for treating inflammation diseases and promoting tissue regeneration. By …

Magnesium (Mg) and its alloys have gained attention for use in orthopedic implants and
bone tissue engineering. However, the corrosion of these materials, which results in toxic by …