TET Enzymes in the Immune system: from DNA demethylation to immunotherapy, inflammation, and cancer

IF López-Moyado, M Ko, PG Hogan… - Annual Review of …, 2024 - annualreviews.org
Ten-eleven translocation (TET) proteins are iron-dependent and α-ketoglutarate-dependent
dioxygenases that sequentially oxidize the methyl group of 5-methylcytosine (5mC) to 5 …

Transcriptomic remodeling of gastric cells by Helicobacter pylori outer membrane vesicles

J Melo, B Cavadas, L Pereira, C Figueiredo… - Helicobacter, 2024 - Wiley Online Library
Abstract Background Outer membrane vesicles (OMVs) are spontaneously released by
Gram‐negative bacteria and influence bacteria‐host interactions by acting as a delivery …

[HTML][HTML] Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation

J Ji, J Cao, P Chen, R Huang, SD Ye - Journal of Biological Chemistry, 2024 - ASBMB
Inhibition of protein kinase C (PKC) efficiently promoted the self-renewal of embryonic stem
cells (ESCs). However, information about the function of PKC inhibition remains lacking …

[HTML][HTML] Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides

AV Endutkin, AV Yudkina, TD Zharkov, AE Barmatov… - Biomolecules, 2024 - mdpi.com
Clickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in
studies of DNA replication in living cells and in DNA functionalization for bionanotechology …

New methods to study DNA methylation and the insights from their application

D Sapozhnikov - 2024 - escholarship.mcgill.ca
DNA methylation is broadly involved in transcriptional regulation across a vast number of
physiological and pathological conditions350. For nearly half a century, it has been widely …