Organ transplantation remains the most optimal strategy for patients with end-stage organ
failure. However, prevailing methods of immunosuppression are marred by adverse side …

Transplanted organs carry donor immune cells into the recipient, the majority of which are
tissue-resident macrophages (TRMs). The role they play in guiding the fate of the …

Chronic kidney disease (CKD) is a chronic and progressive systemic condition that
characterizes irreversible alterations in the kidneys' function and structure over an extended …

Elevated oxidative stress can play a pivotal role in autoimmune diseases by exacerbating
inflammatory responses and tissue damage. In Sjögren's disease (SjD), the contribution of …

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme originally found in
the brain. Our previous work revealed that UCHL1 was also expressed in skeletal muscle …

Inflammation is the tissue's reaction to injurious agents, including sterile inflammation and
infectious inflammation. Identifying the stimuli and examining the physiological status would …

The fundamental causes of cognitive disorders from acute delirium to chronic dementia are
incompletely understood at the level of brain matter, such as neural networks, cells and …

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme that was originally
discovered in neurons. UCHL1 is also expressed in skeletal muscle, but its functions remain …

Introduction The degradation of plastic waste into smaller micro-and nanoplastic (MNPs)
molecules has led to widespread distribution of these particles and accumulation in the …

Inflamasi merupakan reaksi tubuh terhadap rangsangan berbahaya, ditandai dengan
infiltrasi sel radang serta produksi sitokin pro-inflamasi, termasuk TNF-α. Salah satu …