Histone acetylation is highly conserved across eukaryotes and has been linked to gene
activation since its discovery nearly 60 years ago. Over the past decades, histone …

Engineered matrices provide a valuable platform to understand the impact of biophysical
factors on cellular behavior such as migration, proliferation, differentiation, and tissue …

Lysosomal transmembrane acetylation of heparan sulfates (HS) is catalyzed by HS acetyl-
CoA: α-glucosaminide N-acetyltransferase (HGSNAT), whose dysfunction leads to …

Protein acetylation refers to a process of adding acetyl groups (CH3CO-) to lysine residues
on protein chains. As one of the most commonly used protein post-translational …

The fundamental role of cells in safeguarding the genome's integrity against DNA double‐
strand breaks (DSBs) is crucial for maintaining chromatin homeostasis and the overall …

Kinetically inert platinum (IV) complexes are a chemical strategy to overcome the
impediments of standard platinum (II) antineoplastic drugs like cisplatin, oxaliplatin and …

Epigenetic modifications and their alterations can cause variation in gene expression
patterns which can ultimately affect a healthy individual. Until a few years ago, it was thought …

Epigenetics is a branch of molecular biology studying modifications able to change the
expression of genes without altering their DNA sequences. Epigenetic modulations include …

The microbial flora has always been a center of interest for the identification of novel
bioactive secondary metabolites (SMs) used against a diversity of infections and ailments …

While the main primary structure of a protein is regulated by genetic codes whereas its
functionality is mostly controlled by a dynamic transaction in which the functioning of multiple …