The role of histone acetylation in transcriptional regulation and seed development
Y Chen, P Guo, Z Dong - Plant Physiology, 2024 - academic.oup.com
Histone acetylation is highly conserved across eukaryotes and has been linked to gene
activation since its discovery nearly 60 years ago. Over the past decades, histone …
activation since its discovery nearly 60 years ago. Over the past decades, histone …
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs
Engineered matrices provide a valuable platform to understand the impact of biophysical
factors on cellular behavior such as migration, proliferation, differentiation, and tissue …
factors on cellular behavior such as migration, proliferation, differentiation, and tissue …
Structure and mechanism of lysosome transmembrane acetylation by HGSNAT
R Xu, Y Ning, F Ren, C Gu, Z Zhu, X Pan… - Nature Structural & …, 2024 - nature.com
Lysosomal transmembrane acetylation of heparan sulfates (HS) is catalyzed by HS acetyl-
CoA: α-glucosaminide N-acetyltransferase (HGSNAT), whose dysfunction leads to …
CoA: α-glucosaminide N-acetyltransferase (HGSNAT), whose dysfunction leads to …
Protein acetylation sites with complex-valued polynomial model
W Bao, B Yang - Frontiers of Computer Science, 2024 - Springer
Protein acetylation refers to a process of adding acetyl groups (CH3CO-) to lysine residues
on protein chains. As one of the most commonly used protein post-translational …
on protein chains. As one of the most commonly used protein post-translational …
Chromatin lysine acylation: On the path to chromatin homeostasis and genome integrity
F Chen, X He, W Xu, L Zhou, Q Liu, W Chen… - Cancer …, 2024 - Wiley Online Library
The fundamental role of cells in safeguarding the genome's integrity against DNA double‐
strand breaks (DSBs) is crucial for maintaining chromatin homeostasis and the overall …
strand breaks (DSBs) is crucial for maintaining chromatin homeostasis and the overall …
Platinum (IV) Prodrugs Incorporating an Indole-Based Derivative, 5-Benzyloxyindole-3-Acetic Acid in the Axial Position Exhibit Prominent Anticancer Activity
AD Aputen, MG Elias, J Gilbert, JA Sakoff… - International journal of …, 2024 - mdpi.com
Kinetically inert platinum (IV) complexes are a chemical strategy to overcome the
impediments of standard platinum (II) antineoplastic drugs like cisplatin, oxaliplatin and …
impediments of standard platinum (II) antineoplastic drugs like cisplatin, oxaliplatin and …
The interplay of metabolic and epigenetic players in disease development
P Chakraborty, C Mukherjee - Biochemical and Biophysical Research …, 2024 - Elsevier
Epigenetic modifications and their alterations can cause variation in gene expression
patterns which can ultimately affect a healthy individual. Until a few years ago, it was thought …
patterns which can ultimately affect a healthy individual. Until a few years ago, it was thought …
New data on the pathophysiology of ischemic stroke: epigenetic mechanisms in focus
KA Aitbaev, IT Murkamilov, VV Fomin… - Neuroscience and …, 2024 - Springer
Epigenetics is a branch of molecular biology studying modifications able to change the
expression of genes without altering their DNA sequences. Epigenetic modulations include …
expression of genes without altering their DNA sequences. Epigenetic modulations include …
Epigenetic Regulation of Fungal Secondary Metabolites for the Enhancement of Therapeutically Active Compounds
S Prakash, H Kumari, Minakshi, A Kumar - Fungi Bioactive Metabolites …, 2024 - Springer
The microbial flora has always been a center of interest for the identification of novel
bioactive secondary metabolites (SMs) used against a diversity of infections and ailments …
bioactive secondary metabolites (SMs) used against a diversity of infections and ailments …
Post-Translational Modifications in Progression of Ovarian and Prostate Cancer
P Padelkar - … Peer-Reviewed E-Journal-ISSN 2454-8596, 2024 - j.vidhyayanaejournal.org
While the main primary structure of a protein is regulated by genetic codes whereas its
functionality is mostly controlled by a dynamic transaction in which the functioning of multiple …
functionality is mostly controlled by a dynamic transaction in which the functioning of multiple …