Prolonged vs intermittent infusions of β-lactam antibiotics in adults with sepsis or septic shock: a systematic review and meta-analysis

MH Abdul-Aziz, NE Hammond, SJ Brett, MO Cotta… - JAMA, 2024 - jamanetwork.com
Importance There is uncertainty about whether prolonged infusions of β-lactam antibiotics
improve clinically important outcomes in critically ill adults with sepsis or septic shock …

Prolonged versus intermittent β-lactam infusion in sepsis: a systematic review and meta-analysis of randomized controlled trials

Y Zhao, B Zang, Q Wang - Annals of Intensive Care, 2024 - Springer
Background The two latest studies on prolonged versus intermittent use of β-lactam
antibiotics in patients with sepsis did not reach consistent conclusions, further contributing to …

Extended-Infusion β-Lactam Therapy, Mortality, and Subsequent Antibiotic Resistance Among Hospitalized Adults With Gram-Negative Bloodstream Infections

SM Karaba, SE Cosgrove, JH Lee, S Fiawoo… - JAMA Network …, 2024 - jamanetwork.com
Importance Current evidence is conflicting for associations of extended-infusion β-lactam (EI-
BL) therapy with clinical outcomes. Objective To investigate the association of EI-BL therapy …

Detailed regimens for the prolonged β-lactam infusion therapy

H Hagiya - Journal of Infection and Chemotherapy, 2024 - Elsevier
A recent systematic review and meta-analysis of randomized controlled trials (RCTs)
evaluated the efficacy and safety of prolonged versus intermittent β-lactam infusion in adult …

Comment on 'international consensus recommendations for the use of prolonged‐infusion β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP) …

CA Espinoza Cobeñas - Pharmacotherapy: The Journal of …, 2024 - Wiley Online Library
“Comment on ‘international consensus recommendations for the use of prolonged‐infusion
β‐lactams endorsed by the American College of Clinical Pharmacy (ACCP), the British …