Background Post-thrombotic syndrome (PTS) is the main long-term complication of deep
vein thrombosis (DVT). Several therapies are being evaluated to prevent or to treat PTS …

Cardiovascular diseases, among which includes coronary artery disease, represent one of
the most important causes of mortality and morbidity worldwide. Research aimed at …

Background: Direct oral anticoagulants (DOACs) cause unwanted interference in various
hemostasis assays, including lupus anticoagulant (LA) testing, where false positive and …

Background: Despite pregnancy's hypercoagulable state, the correlation between inherited
thrombophilia and thrombotic adverse pregnancy outcomes remains uncertain. The …

Abstract Background and Objectives Deficiencies of protein C (PC) or protein S (PS) are rare
diseases, characterized by mutations in the PC or PS genes, which encode plasma serine …

Introduction The monitoring of unfractionated heparin (UFH) by anti‐factor Xa activity (AXA)
is commonly used to ensure effective anticoagulation and prevent bleeding risk. However, in …

Venous thromboembolism (VTE) is a multifactorial disease arising from a complex interplay
between acquired clinical risk factors and inherited genetic predispositions. VTE is a …

Background Inherited antithrombin (AT) deficiency (ATD) is a severe thrombophilia causing
venous thromboembolism, which can be complicated by postthrombotic syndrome (PTS) …

Background: Thrombophilia is a coagulation disorder closely associated with venous
thromboembolism. Hereditary antithrombin III (AT III) deficiency is a type of genetic …

Background: A category of hereditary diseases known as Thrombophilia induces irregular
blood clotting. Pre-eclampsia, late miscarriages, premature delivery, fetal growth restriction …