As an important proangiogenic factor, platelet-derived growth factor (PDGF) and its receptor
PDGFR are highly expressed in a variety of tumors, fibrosis, cardiovascular and …

Mineralocorticoid excess commonly leads to hypertension (HTN) and kidney disease. In our
study, we used single-cell expression and chromatin accessibility tools to characterize the …

Fibrosis, which causes structural hardening and functional degeneration in various organs,
is characterized by the excessive production and accumulation of connective tissue …

Interstitial lung diseases comprise a heterogenous range of diffuse lung disorders,
potentially resulting in pulmonary fibrosis. While idiopathic pulmonary fibrosis has been …

Diabetic kidney disease (DKD) is a leading cause of kidney failure. However, the
involvement of renal fibroblasts and their communications with renal epithelial cells during …

Background Diabetic cardiomyopathy (DCM) poses a growing health threat, elevating heart
failure risk in diabetic individuals. Understanding DCM is crucial, with fibroblasts and …

Fibrosis-related diseases (FRD) include conditions like myocardial fibrosis, pulmonary
fibrosis, hepatic fibrosis, renal fibrosis, and others. The impact of fibrosis can be severe …

Purpose Hepatic fibrosis develops as a response to chronic liver injury, resulting in the
formation of fibrous scars. This process is initiated and driven by collagen-producing …

Alport syndrome is an inherited kidney disease, which can lead to glomerulosclerosis and
fibrosis, as well as end-stage kidney disease in children and adults. Platelet-derived growth …

Introduction: Yinchenzhufu decoction (YCZFD) is a traditional Chinese medicine formula
with hepatoprotective effects. In this study, the protective effects of YCZFD against …