Optimization of Ethoxzolamide Analogs with Improved Pharmacokinetic Properties for In Vivo Efficacy against Neisseria gonorrhoeae

MS Youse, NS Abutaleb, A Nocentini… - Journal of Medicinal …, 2024 - ACS Publications
Drug-resistant gonorrhea is caused by the bacterial pathogen Neisseria gonorrhoeae, for
which there is no recommended oral treatment. We have demonstrated that the FDA …

Characterization of Neisseria gonorrhoeae colonization of macrophages under distinct polarization states and nutrients environment

MD Juárez Rodríguez, M Marquette… - Frontiers in Cellular …, 2024 - frontiersin.org
Neisseria gonorrhoeae (Ng) is a uniquely adapted human pathogen and the etiological
agent of gonorrhea, a sexually transmitted disease. Ng has developed numerous …

Neisseria gonorrhoeae

L Qian, GG McSheffrey, SD Gray-Owen… - Molecular Medical …, 2024 - Elsevier
Gonorrhea has been with man since antiquity, being mentioned in the Book of Leviticus of
the Bible and in ancient Chinese writings. Hippocrates, who referred to gonorrhea as …

Adjuvant-dependent impacts on vaccine-induced humoral responses and protection in preclinical models of nasal and genital colonization by pathogenic Neisseria

EA Islam, JE Fegan, JJ Zeppa, SK Ahn, D Ng… - bioRxiv, 2024 - biorxiv.org
Neisseria gonorrhoeae, which causes the sexually transmitted infection gonorrhea and N.
meningitidis, a leading cause of bacterial meningitis and septicemia, are closely related …

EXPLORING PAIN FREE VACCINATION ALTERNATIVES FOR A WHOLE CELL INACTIVATED MICROPARTICULATE GONORRHEA VACCINE

PV Bagwe - 2024 - ursa.mercer.edu
There is a global rise in the number of cases of gonorrhea infection each year. Gonorrhea is
caused by the bacteria Neisseria gonorrhoeae and is currently being treated using …