Hip fractures are associated with significant disability, high cost, and mortality. However, the
exact biological mechanisms underlying susceptibility to hip fractures remain incompletely …

Clinical genetic testing may identify the appropriate diagnosis in a subset of patients with
low bone mass, multiple or unusual fractures, and severe or early-onset osteoporosis, and …

Osteogenesis imperfecta (OI) is a heterogeneous spectrum of hereditary genetic disorders
that cause bone fragility, through various quantitative and qualitative defects of type 1 …

We and others have shown that application of high-level mechanical loading promotes the
formation of transient plasma membrane disruptions (PMD) which initiate …

Purpose The purpose of this study was to identify new independent significant SNPs
associated with osteoporosis using data from the Taiwan Biobank (TWBB). Material and …

Bone toxicities are common among paediatric patients treated for acute lymphoblastic
leukaemia (ALL) with potentially major negative impact on patients' quality of life. To identify …

Background Epithelial stromal interaction 1 (EPSTI1) plays an important role in M1
macrophages, which induce osteoclastogenesis. One recent genome-wide association …

The association between interleukins and osteoporosis has attracted much attention these
days. However, the causal relationship between them is uncertain. Hence, this study …

Vitamin D has important roles in calcium metabolism and in the prevention of rickets and
osteomalacia. There is also increasing evidence to suggest a role for vitamin D in …

Key Clinical Message Whole‐exome sequencing (WES) analysis of an expansive case florid
cemento‐osseus dysplasia were reported for the first time. Also, the new potential candidate …