Actinomycin D synergizes with Doxorubicin in triple-negative breast cancer by inducing P53-dependent cell apoptosis

H Yang, S Li, W Li, Y Yang, Y Zhang, S Zhang… - …, 2024 - academic.oup.com
Objectives There are three major subtypes of breast cancer, ER+, HER2+ and triple-
negative breast cancer (TNBC), namely ER−, PR−, HER2−. TNBC is the most aggressive …

[HTML][HTML] Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

T Isermann, KL Schneider, F Wegwitz, T De Oliveira… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The stress-associated molecular chaperone system is an actionable target in cancer
therapies. It is ubiquitously upregulated in cancer tissues and enables tumorigenicity by …