Bivalirudin versus unfractionated heparin in patients with myocardial infarction undergoing percutaneous coronary intervention: A systematic review and meta …

A Al-Abdouh, M Mhanna, A Jabri, L Madanat… - Cardiovascular …, 2024 - Elsevier
Background Bivalirudin is an alternative accepted therapy to unfractionated heparin for
patients with myocardial infarction (MI) undergoing percutaneous coronary intervention …

An update on oral antiplatelet drug interactions with proton pump inhibitors: what are the risks?

G Jourdi, JS Hulot, P Gaussem - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Aspirin and anti-P2Y12 are widely prescribed in cardiovascular patients, often
in combination with proton pump inhibitors (PPIs) to limit the risk of upper gastrointestinal …

Extended clopidogrel monotherapy vs DAPT in patients with acute coronary syndromes at high ischemic and bleeding risk: the OPT-BIRISK randomized clinical trial

Y Li, J Li, B Wang, Q Jing, Y Zeng, A Hou… - JAMA …, 2024 - jamanetwork.com
Importance Purinergic receptor P2Y12 (P2Y12) inhibitor monotherapy after a certain period
of dual antiplatelet therapy (DAPT) may be an attractive option of maintenance antiplatelet …

Anti-thrombotic effects mediated by a novel dual-target peptide inhibiting both platelet aggregation and thrombin activity without causing bleeding

J Yu, T Wang, X Zhang, Q Chen, Y Hu… - Thrombosis and …, 2024 - thieme-connect.com
Background Classical anticoagulants and antiplatelets are associated with high frequencies
of bleeding complications or treatment failure when used as single agents. Thrombin plays …

Ticagrelor or prasugrel vs. clopidogrel in patients with atrial fibrillation undergoing percutaneous coronary intervention for myocardial infarction

SJ Godtfredsen, KH Kragholm… - … heart journal open, 2024 - academic.oup.com
Aims The efficacy and safety of ticagrelor or prasugrel vs. clopidogrel in patients with atrial
fibrillation (AF) on oral anticoagulation (OAC) undergoing percutaneous coronary …

Post-procedural Anticoagulation With Unfractionated Heparin in Acute Coronary Syndrome: Insight from the STOPDAPT-3 Trial

H Watanabe, M Natsuaki, T Morimoto… - The American Journal of …, 2024 - Elsevier
The current guidelines for acute coronary syndrome (ACS) discourage the use of
anticoagulation after percutaneous coronary intervention (PCI) without specific indications …

[HTML][HTML] WY-14643, a novel antiplatelet and antithrombotic agent targeting the GPIbα receptor

C Cao, Q Yang, X Xia, Z Chen, P Liu, X Wu, H Hu… - Thrombosis …, 2024 - Elsevier
Background and purpose Hypolipidemia and platelet activation play key roles in
atherosclerotic diseases. Pirinixic acid (WY-14643) was originally developed as a lipid …

Pre-hospital admission of heparin in patients with suspected non-ST segment elevation acute coronary syndrome

J Sundermeyer, A Schock, C Kellner, PM Haller… - Clinical Research in …, 2024 - Springer
Background Evidence supporting pre-hospital heparin administration in patients with
suspected non-ST segment elevation acute coronary syndrome (NSTE-ACS) is lacking. We …

[HTML][HTML] Anticoagulative activity of Commiphora gileadensis, aspirin, and heparin on blood coagulation profiles in naïve mice

AS Alhazmi - International Journal of Health Sciences, 2024 - ncbi.nlm.nih.gov
Objective: Commiphora gileadensis is a small tree under the genus Commiphora. Previous
studies showed medical applications, such as antibacterial and antihypertensive, for C …

[HTML][HTML] Invasive and conservative management of elderly patients presenting with acute coronary syndrome: A meta-analysis of randomized controlled trials and …

R Improta, G Di Pietro, A Piccialuti, O De Filippo… - International Journal of …, 2024 - Elsevier
Background Elderly patients are often under-represented in studies about coronary
revascularization in acute coronary syndromes (ACS) and undertreated in clinical practice …