Although it is well described that mitochondria are at the epicentre of the energy demands of
a cell, it is becoming important to consider how each cell tailors its mitochondrial …

Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable
plasticity and play pivotal roles in coordinating immune responses and maintaining tissue …

Background: The impairment in ATP production and transport in renal proximal tubule cells
(RPTCs) has been linked to the pathogenesis of obesity-induced chronic kidney disease …

Adenosine nucleotide translocases (ANTs) are a family of proteins abundant in the inner
mitochondrial membrane, primarily responsible for shuttling ADP and ATP across the …

White adipose tissue accumulation and inflammation contribute to obesity by inducing
insulin resistance. Herein, we aimed to screen the synergistic components of the herbal pair …

Obesity per se is rapidly emerging all over the planet and further accounts for many other life-
threatening conditions, such as diabetes, cardiovascular diseases, and cancers. Decreased …

Microcirculatory dysfunction has been observed in the dermal white adipose tissue (dWAT)
and subcutaneous white adipose tissue (scWAT) of obese humans and has been proposed …

Background Obesity is associated with extensive white adipose tissue (WAT) expansion and
remodeling. Healthy WAT expansion contributes to the maintenance of energy balance in …

Obesity, a rapidly expanding epidemic worldwide, is known to exacerbate many medical
conditions, making it a significant factor in multiple diseases and their associated …

Dermal white adipose tissue may participate in the wound-healing process. Obesity-
mediated chronic low-grade inflammation impairs wound healing by suppressing …