Toward identifying key mechanisms of progression in multiple sclerosis
L Husseini, A Geladaris, MS Weber - Trends in Neurosciences, 2024 - cell.com
A major therapeutic goal in the treatment of multiple sclerosis (MS) is to prevent the
accumulation of disability over an often decades-long disease course. Disability progression …
accumulation of disability over an often decades-long disease course. Disability progression …
Clinical impact of gender and age at onset on disease trajectory in primary progressive multiple sclerosis patients
S Camerlingo, F Rubinstein… - Multiple Sclerosis …, 2024 - journals.sagepub.com
Background and Objectives: Primary-progressive multiple sclerosis (PPMS) is characterized
by gradual neurological deterioration without relapses. This study aimed to investigate the …
by gradual neurological deterioration without relapses. This study aimed to investigate the …
Prospective observational study to evaluate treatment satisfaction and effectiveness in patients with relapsing multiple sclerosis starting cladribine tablets (CLADREAL …
M Filippi, L Ferrè, C Zanetta, C Rizzi, G Pessina… - Frontiers in …, 2024 - frontiersin.org
Disease-modifying therapies (DMTs) for multiple sclerosis (MS) reduce relapse frequency,
magnetic resonance imaging (MRI) activity, and slow disability progression. Numerous …
magnetic resonance imaging (MRI) activity, and slow disability progression. Numerous …
A mixture model for differentiating longitudinal courses of multiple sclerosis
FTL de Menezes, AB Lopes, JMD Alencar… - Multiple Sclerosis and …, 2024 - Elsevier
Background Multiple sclerosis has a broad spectrum of clinical courses. Early identification
of patients at greater risk of accumulating disability is essential. Objectives Identify groups of …
of patients at greater risk of accumulating disability is essential. Objectives Identify groups of …
Stochastic models for the onset and disease course of multiple sclerosis
T Akaishi, T Misu, T Takahashi, K Fujihara… - Clinical Neurology and …, 2024 - Elsevier
Objective Exact causes and mechanisms regulating the onset and progression in many
chronic diseases, including multiple sclerosis (MS), remain uncertain. Until now, the …
chronic diseases, including multiple sclerosis (MS), remain uncertain. Until now, the …