Proactive Versus Reactive Control Strategies Differentially Mediate Alcohol Drinking in Male Wistars and P Rats
MD Morningstar, NM Timme, B Ma, E Cornwell… - Eneuro, 2024 - eneuro.org
Problematic alcohol consumption is associated with deficits in decision-making and
alterations in prefrontal cortex neural activity likely contribute. We hypothesized that the …
alterations in prefrontal cortex neural activity likely contribute. We hypothesized that the …
Altered structural connectivity and functional brain dynamics in individuals with heavy alcohol use elucidated via network control theory
SP Singleton, P Velidi, L Schilling, AI Luppi… - Biological Psychiatry …, 2024 - Elsevier
Background Heavy alcohol use (HAU) and its associated conditions, such as alcohol use
disorder (AUD), impact millions of individuals worldwide. While our understanding of the …
disorder (AUD), impact millions of individuals worldwide. While our understanding of the …
Altered reward sensitivity to sucrose outcomes prior to drug exposure in alcohol preferring rats
JJ McGraw, RS Goldsmith, HC Cromwell - Pharmacology Biochemistry and …, 2024 - Elsevier
Addiction involves key impairments in reward sensitivity (RS). The current study explored
impaired RS to natural reward as a predisposing factor to addictive-like behavior. Alcohol …
impaired RS to natural reward as a predisposing factor to addictive-like behavior. Alcohol …
[HTML][HTML] Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum
Lack of cognitive flexibility is a hallmark of substance use disorders and has been
associated with drug-induced synaptic plasticity in the dorsomedial striatum (DMS). Yet the …
associated with drug-induced synaptic plasticity in the dorsomedial striatum (DMS). Yet the …