Using Liver Organoids as Models to Study the Pathobiology of Rare Liver Diseases
DA Obeid, TA Mir, A Alzhrani, A Altuhami, T Shamma… - Biomedicines, 2024 - mdpi.com
Liver organoids take advantage of several important features of pluripotent stem cells that
self-assemble in a three-dimensional culture matrix and reproduce many aspects of the …
self-assemble in a three-dimensional culture matrix and reproduce many aspects of the …
Bioengineered Organoids Offer New Possibilities for Liver Cancer Studies: A Review of Key Milestones and Challenges
A Jabri, J Khan, B Taftafa, M Alsharif, A Mhannayeh… - Bioengineering, 2024 - mdpi.com
Hepatic cancer is widely regarded as the leading cause of cancer-related mortality
worldwide. Despite recent advances in treatment options, the prognosis of liver cancer …
worldwide. Despite recent advances in treatment options, the prognosis of liver cancer …
Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes
L Große-Segerath, P Follert, K Behnke, J Ettich… - Nature …, 2024 - nature.com
Recently, we have shown that after partial hepatectomy (PHx), an increased hepatic blood
flow initiates liver growth in mice by vasodilation and mechanically-triggered release of …
flow initiates liver growth in mice by vasodilation and mechanically-triggered release of …
肿瘤类器官及其在合成生物学中的研究进展
孟倩， 尹聪， 黄卫人 - 合成生物学, 2024 - synbioj.cip.com.cn
类器官技术的发展为更接近机体细胞组成和病理生理特征的癌症模型开辟了新途径.
患者来源的肿瘤类器官在多次传代后仍能维持原有肿瘤的组织病理学及遗传表型特征 …
患者来源的肿瘤类器官在多次传代后仍能维持原有肿瘤的组织病理学及遗传表型特征 …
Rapid Self‐Assembly Mini‐Livers Protect Mice Against Severe Hepatectomy‐Induced Liver Failure
M Luo, J Lai, E Zhang, Y Ma, R He, L Mao… - Advanced …, 2024 - Wiley Online Library
The construction of bioartificial livers, such as liver organoids, offers significant promise for
disease modeling, drug development, and regenerative medicine. However, existing …
disease modeling, drug development, and regenerative medicine. However, existing …
Establishment of a cell culture platform for human liver organoids and its application for lipid metabolism research
A Kuboyama‐Sasaki, Y Takahashi, C Xia… - Biotechnology …, 2024 - Wiley Online Library
Human liver organoids (HLOs) are reliable tools to represent physiological human liver
biology. However, their use is limited especially in basic sciences. One of the reasons for …
biology. However, their use is limited especially in basic sciences. One of the reasons for …
Acoustic levitation as a tool for cell‐driven self‐organization of human cell spheroids during long‐term 3D culture
L Rabiet, L Arakelian, N Jeger‐Madiot… - Biotechnology and …, 2024 - Wiley Online Library
Acoustic levitation, which allows contactless manipulation of micro‐objects with ultrasounds,
is a promising technique for spheroids formation and culture. This acoustofluidic technique …
is a promising technique for spheroids formation and culture. This acoustofluidic technique …
Establishment of human induced pluripotent stem cell-derived hepatobiliary organoid with bile duct for pharmaceutical research use
L Wang, Y Koui, K Kanegae, T Kido, M Tamura-Nakano… - Biomaterials, 2024 - Elsevier
In vitro models of the human liver are promising alternatives to animal tests for drug
development. Currently, primary human hepatocytes (PHHs) are preferred for …
development. Currently, primary human hepatocytes (PHHs) are preferred for …
[HTML][HTML] 肝脏类器官研究的文献计量学分析
徐灿丽， 何文星， 汪磊， 吴芳婷， 王佳慧， 段雪琳… - 中国组织工程研究, 2024 - cjter.com
肝脏类器官研究的文献计量学分析 中国组织工程研究 首页 关于本刊 编委会 在线投稿 期刊公告
出版道德 OA政策 作者学院 在线问答 联系我们 English 中国组织工程研究 ›› 2024, Vol. 28 ›› …
出版道德 OA政策 作者学院 在线问答 联系我们 English 中国组织工程研究 ›› 2024, Vol. 28 ›› …
[HTML][HTML] Human brain organoid: trends, evolution, and remaining challenges
Advanced brain organoids provide promising platforms for deciphering the cellular and
molecular processes of human neural development and diseases. Although various studies …
molecular processes of human neural development and diseases. Although various studies …